Results 21 to 30 of about 10,233 (159)

Some anticancer agents as effective glutathione S-transferase (GST) inhibitors

open access: yesOpen Chemistry, 2023
The objective of this research was to investigate the impact of anthraquinone (AQ) compounds on the activity of the enzyme glutathione S-transferase (GST).
Gökçe Başak
doaj   +1 more source

Phytochemical and antifungal activity of anthraquinones and root and leaf extracts of Coccoloba mollis on phytopathogens

open access: yesBrazilian Archives of Biology and Technology, 2011
The aim of this work was to study the phytochemical and antifungal activity of anthraquinones and root and leaf extracts of Coccoloba mollis on phytopathogens.
Iuri Bezerra de Barros   +5 more
doaj   +1 more source

Emodin-8-O-Glucoside—Isolation and the Screening of the Anticancer Potential against the Nervous System Tumors

open access: yesMolecules, 2023
Emodin-8-O-glucoside (E-8-O-G) is a glycosylated derivative of emodin that exhibits numerous biological activities, including immunomodulatory, anti-inflammatory, antioxidant, hepatoprotective, or anticancer activities.
Estera Okon   +7 more
doaj   +1 more source

Anthraquinones as Inhibitors of SOS RAS-GEF Activity

open access: yesBiomolecules, 2021
Recent breakthroughs have reignited interest in RAS GEFs as direct therapeutic targets. To search for new inhibitors of SOS GEF activity, a repository of known/approved compounds (NIH-NACTS) and a library of new marine compounds (Biomar Microbial ...
Alberto Fernández-Medarde   +6 more
doaj   +1 more source

Anthraquinones tautomerism: VII. Hydroxy-substituted anthraquinones

open access: yesRussian Journal of Organic Chemistry, 2007
Tautomerism of β-mono-, β,β'-dihydroxyanthraquinones, and their anions was studied for the first time by quantum-chemical and correlation methods. 2-Hydroxyanthraquinone exists exclusively in 9,10-quinoid form, and its ionization involves a tautomeric transformation into 10-oxido-2,9- anthraquinone.
Fain V.Ya., Zaitsev B.E., Ryabov M.A.
openaire   +3 more sources

Constituintes químicos do caule de Senna reticulata Willd. (Leguminoseae): Chemical constituents isolated from the wood of Senna reticulata Willd.

open access: yesQuímica Nova, 2008
The phytochemical investigation of the wood extracts of Senna reticulata (Leguminoseae) yielded six anthraquinones: chrysophanol, physcion, aloe-emodin, 1,3,8-trihydroxyanthraquinone, 3-methoxy-1,6,8-trihydroxyanthraquinone, emodin and the chrysophanol ...
Rogério Nunes dos Santos   +2 more
doaj   +1 more source

Role of anthraquinones in combating insulin resistance

open access: yesFrontiers in Pharmacology, 2023
Insulin resistance presents a formidable public health challenge that is intricately linked to the onset and progression of various chronic ailments, including diabetes, cardiovascular disease, hypertension, metabolic syndrome, nonalcoholic fatty liver ...
Wanru Xia   +8 more
doaj   +1 more source

Chemical Diversity and Biological Activities of Phaeosphaeria Fungi Genus: A Systematic Review

open access: yesJournal of Fungi, 2018
Microbial natural products (MNPs) have been identified as important hotspots and effective sources for drug lead discovery. The genus Phaeosphaeria (family: Phaeosphaeriaceae, order: Pleosporales), in particular, has produced divergent chemical ...
Amr El-Demerdash
doaj   +1 more source

HPTLC-DESI-HRMS-Based Profiling of Anthraquinones in Complex Mixtures—A Proof-of-Concept Study Using Crude Extracts of Chilean Mushrooms

open access: yesFoods, 2020
High-performance thin-layer chromatography (HPTLC) coupled with negative ion desorption electrospray ionization high-resolution mass spectrometry (DESI-HRMS) was used for the analysis of anthraquinones in complex crude extracts of Chilean dermocyboid ...
Annegret Laub   +5 more
doaj   +1 more source

Increased Free Radical Generation during the Interaction of a Quinone-Quinoline Chelator with Metal Ions and the Enhancing Effect of Light

open access: yesPharmaceuticals, 2023
Schiff bases and similar molecules forming metal complexes may cause redox effects, which may also be influenced by light. Anthraquinones such as doxorubicin and idarubicin are widely used antitumor agents, which can generate reactive oxygen species (ROS)
Olga Yu. Selyutina   +4 more
doaj   +1 more source

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