Results 131 to 140 of about 12,330,460 (352)

A Review of Deep Learning Techniques for Leukemia Cancer Classification Based on Blood Smear Images

Applied Biosciences
This research reviews deep learning methodologies for detecting leukemia, a critical cancer diagnosis and treatment aspect. Using a systematic mapping study (SMS) and systematic literature review (SLR), thirty articles published between 2019 and 2023 ...
Rakhmonalieva Farangis Oybek Kizi, Tagne Poupi Theodore Armand, Hee-Cheol Kim   +2 more
doaj   +1 more source

Making More Efficient the Dissemination of the Information in the Field of Anti-Aging through Information Technology [PDF]

ICT have become extremely important because they allow everybody to participate at the Information Society, in spite of under-privileged personal or social situation.
Marilena IANCULESCU, Monica PARVAN
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Melatonin use in sleep disorders [PDF]

, 1997
Melatonin is a widely publicized 'magical drug'. Claims of its use include regulation of sleep, circadian rhythm, mood, immune system and reproduction, anti-aging, protection against cancer, and treatment of AIDS. This article reviews the evidence of its
Chung, KF
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Lightweight Deep Learning and Sorting-Based Smart Parking System for Real-Time Edge Deployment

AppliedMath
As cities grow denser, the demand for efficient parking systems becomes more critical to reduce traffic congestion, fuel consumption, and environmental impact.
Muhammad Omair Khan, Muhammad Asif Raza, Md Ariful Islam Mozumder, Ibad Ullah Azam, Rashadul Islam Sumon, Hee Cheol Kim   +5 more
doaj   +1 more source

Multiple discrete soluble aggregates influence polyglutamine toxicity in a Huntington\u27s disease model system [PDF]

, 2016
Huntington’s disease (HD) results from expansions of polyglutamine stretches (polyQ) in the huntingtin protein (Htt) that promote protein aggregation, neurodegeneration, and death.
Denis, Clyde L., Wang, Xin, Xi, Wen
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Acetyl genistin modulates myotube differentiation and attenuates dexamethasone-induced muscle atrophy through the FoxO1/3 signaling pathway in C2C12 myotubes

Applied Biological Chemistry
Muscle atrophy, a debilitating condition characterized by loss of muscle mass and strength, is a major concern in various clinical settings. Acetyl genistin (AG), a bioactive compound, was evaluated for its role in muscle cell differentiation and its ...
Won Min Jeong, Seung-Jin Kwag, Jun Young Ha, Seung-Jun Lee, Yeong-In Choe, Dong Yeol Lee, Dong Kyu Jeong, Hwan Hee Bae, Jin-Hee Seo, Young-Sool Hah, Sang Gon Kim   +10 more
doaj   +1 more source

Us, Them, and Me! Intergroup and personal challenges of aging successfully [PDF]

, 2017
This Keynote Address was delivered at the 73 rd . Annual New York State Communication Association Conference on October 16, 2015. After an anecdotal foray into how he came to study “geronto-communication”, Dr.
Giles, Howie
core   +1 more source