Results 111 to 120 of about 2,894,735 (305)

Anti-aging Drugs

open access: yes, 2017
Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches.

core   +1 more source

Precision design of dissolving microneedles via mechanically induced micro-vent and Capillary-Controlled Molding: From fabrication to mechanical characterization

open access: yesMaterials & Design
Dissolving microneedles with controlled geometry are difficult to fabricate reproducibly because liquid polydimethylsiloxane (PDMS) molding is prone to meniscus failure and bubble entrapment. Here, we formed a PDMS master mold by directly inserting metal
Sangjun Pyo   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Aging in place begins in the bathroom

open access: yes, 2012
Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.

core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

[Photograph of Officers of the Coalition for Aging LGBT]

open access: yes
Color photograph of Officers of the Coalition for Aging LGBT and offices of The Dallas Way at the 2023 Legacy Dinner for Lambda Legal from the Coalition for Aging LGBT Records (The Dallas Way)
Colaition for Aging LGBT
core  

Vision care - like aging - is everybody's business

open access: yes, 2012
Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.
Davis, Jackie
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Anti-Aging Medicine – Chance for Active Senility

open access: yes, 2013
Introduction. Aging is a general property of all living and non-living systems, which represents the accumulation of violations of the structure and reduction of the function of the system. These changes develop over time.
Korost Ya., Barna O., Getman O.
core   +1 more source

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