Results 91 to 100 of about 2,894,735 (305)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Be the voice. Take action. Tigether
, 2012 Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.
Western Reserve Area Agency on Aging +1 more
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IoMT and Blockchain Synergy: A Novel Approach to Health Data Validation and Storage
IEEE AccessThe increasing adoption of Internet of Medical Things (IoMT) devices is revolutionizing healthcare, facilitating enhanced remote patient monitoring and data-driven clinical decision-making.
Abbas Syed Muhammad Ali +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
[Coalition for Aging LGBT General Preparation Resources]
Coalition for Aging LGBT General Preparation Resources document from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging LGBT
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Anti-aging and successful aging
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2009 社会の高齢化に伴い，加齢により生ずる機能異常，健康障害，疾患に対する対策が急務となっている．動脈硬化症，認知症，骨粗鬆症をはじめとする老年病等の疾患は，それが確定した段階から介入する立場をとると，健康な状態に復帰するために困難が伴うことが多い．そこで，疾患にいたる以前の状態から，予防医学の考えを取り入れて，加齢に伴う機能異常ならびに健康障害にブレーキをかけていく，抗加齢，すなわちアンチエイジングの考えが21世紀に入り脚光を浴びている．一方で，加齢に伴う現象は正常な変化であることを受け入れ，病的な障害を最小限とし，社会的，心理的にも満足がいく状況が望ましいとするサクセスフルエイジングという考えも注目されている．どちらの立場も健康長寿を目指すことに変わりなく，その科学的根拠の基づく実証が求められている．
openaire +3 more sources
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
, 1994 "I am happy to present to you the 1992-93 Annual Report of the Kansas State Advisory Council on Aging"."--[February 3, 1994 Cover letter from Charles Oldfather, Chair of the Council, to Governor Finney et al.]<br>Created in 1977 by the Kansas Act ...
Kansas Advisory Council on Aging.
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