Results 91 to 100 of about 12,330,460 (352)
Fifty-kDa Hyaluronic Acid Upregulates Some Epidermal Genes without Changing TNF-α Expression in Reconstituted Epidermis [PDF]
, 2011 Background: Due to its strong water binding potential, hyaluronic acid (HA) is a well-known active ingredient for cosmetic applications. However, based on its varying molecular size, skin penetration of HA may be limited. Recent studies have demonstrated
B. Malle +15 more
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Interleukin‐36α as a potential biomarker for renal tubular damage induced by dietary phosphate load
FEBS Open Bio, 2020 Excessive intake of phosphate has been known to induce renal tubular damage and interstitial inflammation, leading to acute kidney injury or chronic kidney disease in rodents and humans.
Yoshitaka Hirano +5 more
doaj +1 more source
Death Under Control: The Portrayal of Death in Mass Print English Language Magazines in Canada [PDF]
, 2005 The purpose of this article is to discuss the portrayal of death in modern North American society in the highest circulating English language magazines available in Canada and published either in the United States or in Canada, in 1991, 1996, and 2001 ...
Clarke, Juanne Nancarrow
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Asian Journal of Medical Sciences, 2020 Background: Alcohol consumption does not result in dependence or abuse among most people. Nevertheless, a significant group of the population as a whole unavoidably is troubled by chronic alcoholism.Alcohol is involved in a number of diseases, disorders,
Vachrintr Sirisapsombat +6 more
doaj +1 more source
Systemic Problems: A perspective on stem cell aging and rejuvenation. [PDF]
, 2015 This review provides balanced analysis of the advances in systemic regulation of young and old tissue stem cells and suggests strategies for accelerating development of therapies to broadly combat age-related tissue degenerative pathologies.
CONBOY, Irina M +2 more
core +2 more sources
Nanoparticles-based anti-aging treatment of Alzheimer’s disease
Drug Delivery, 2022 Age is the strongest risk factor for Alzheimer’s disease (AD). In recent years, the relationship between aging and AD has been widely studied, with anti-aging therapeutics as the treatment for AD being one of the mainstream research directions ...
Jianjian Chu +9 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Asian Journal of Medical Sciences, 2020 Background: The present study proposes a task-dependent hypothesis in which the phonological units of segmental (e.g., consonant and vowel) and suprasegmental (e.g., prosodic) are processed in discrete asymmetry of the human brain.
Phakkharawat Sittiprapaporn
doaj +1 more source