Results 71 to 80 of about 12,330,460 (352)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Automated Pipeline for Robust Cat Activity Detection Based on Deep Learning and Wearable Sensor Data

Sensors
The health, safety, and well-being of household pets such as cats has become a challenging task in previous years. To estimate a cat’s behavior, objective observations of both the frequency and variability of specific behavior traits are required, which ...
Md Ariful Islam Mozumder, Tagne Poupi Theodore Armand, Rashadul Islam Sumon, Shah Muhammad Imtiyaj Uddin, Hee-Cheol Kim   +4 more
doaj   +1 more source

Anti-Aging Drugs and the Related Signal Pathways

Biomedicines
Aging is a multifactorial biological process involving chronic diseases that manifest from the molecular level to the systemic level. From its inception to 31 May 2022, this study searched the PubMed, Web of Science, EBSCO, and Cochrane library databases
Nannan Du, Ruigang Yang, Sheng-Ming Jiang, Z. Niu, Wenzhao Zhou, Chenyu Liu, Lihua Gao, Qiang Sun   +7 more
semanticscholar   +1 more source

Antioxidants in Age-Related Diseases and Anti-Aging Strategies

Antioxidants, 2022
Aging is an intricate process and an important risk factor in the development and advancement of many disorders [...].
Marius Emil Rusu, Ionel Fizeșan, L. Vlase, D. Popa   +3 more
semanticscholar   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Stress reduction by Phochong chanting indexed by Thai Stress Test

Asian Journal of Medical Sciences, 2019
Background: Stress is traditionally defined as either a bodily or mental tension resulting from factors that tend to alter an existent equilibrium or the process of appraising events of assessing potential responses, and of responses which may include ...
Jidapa Kerdsurivong, Jarasphol Rintra, Karnt Wongsuphasawat , Phakkharawat Sittiprapaporn   +3 more
doaj   +1 more source

Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway. [PDF]

, 2020
Nutrients are absorbed solely by the intestinal villi. Aging of this organ causes malabsorption and associated illnesses, yet its aging mechanisms remain unclear.
Chen, Ye-Guang, De Pinho, Ronald A, Habib, Samy L, He, Dan, Li, Baojie, Liu, Huijuan, Peng, Peike, Ruan, Xinsen, Ruan, Yuanyuan, Wang, Yibin, Wu, Hongguang, Xiang, Jinnan, Yu, Qiang, Zhang, Hongbing   +13 more
core  

β-hydroxybutyrate as an Anti-Aging Metabolite

Nutrients, 2021
The ketone bodies, especially β-hydroxybutyrate (β-HB), derive from fatty acid oxidation and alternatively serve as a fuel source for peripheral tissues including the brain, heart, and skeletal muscle.
Liankun Wang, Peijie Chen, W. Xiao
semanticscholar   +1 more source

“Anti-aging”: A misnomer? [PDF]

Aesthetic Surgery Journal, 2002
An increasing number of articles and continuing education programs seem to suggest that my cosmetic practice cannot be truly “state-of-the-art” unless it includes an “anti-aging program.” The idea has a certain appeal. I would be doing a real service to my patients if, in fact, such a program could actually prevent or retard aging (and I would make a ...
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source