Results 51 to 60 of about 2,202,587 (262)

Inflammation—Cause or consequence of late onset Alzheimer’s disease or both? A review of the evidence

open access: yesEuropean Journal of Inflammation, 2022
Accumulating evidence suggests that inflammation is involved in the development of late onset Alzheimer’s disease (LOAD). However, it is not clear whether inflammation is a cause or consequence, or both.
Jinrong Zhao   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

BFLIDS: Blockchain-Driven Federated Learning for Intrusion Detection in IoMT Networks

open access: yesSensors
The Internet of Medical Things (IoMT) has significantly advanced healthcare, but it has also brought about critical security challenges. Traditional security solutions struggle to keep pace with the dynamic and interconnected nature of IoMT systems ...
Khadija Begum   +3 more
doaj   +1 more source

Fabrication of a Pneumatic Microparticle Concentrator

open access: yesMicromachines, 2019
We developed a microfluidic platform employing (normally open) pneumatic valves for particle concentration. The device features a three-dimensional network with a curved fluidic channel and three pneumatic valves (a sieve valve (Vs) that concentrates ...
Jun Ho Jang, Ok Chan Jeong
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Aging is a process that should be celebrated every day

open access: yes, 2012
Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.
Matura, Pamela K.   +1 more
core  

The problem of biology and anti-aging: A critical commentary [PDF]

open access: yes, 2017
This year saw more anti-aging researchers talk about providing a 'cure' for aging in the next five years. Recently, this has been taken up by a number of people who could be called "anti-aging pioneers” (Powell, 2005). One of the fundamental continuities
Powell, Jason   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Aging connection (Columbus, Ohio : Online)

open access: yes, 2006
Monthly; Electronic coverage as of May 22, 2007: Mar. 2006-; Description based on Mar. 2006; title from Web page (viewed on May 22, 2007).; Harvested from the web on 5/22/07June 2006, Ohio Leads Nation in Senior Services Levy Revenue. Department of Aging
Ohio. Dept. of Aging
core  

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