Results 41 to 50 of about 2,894,735 (305)
HeliyonBaseball is rapidly growing in global popularity, making accurate ball detection and pitch evaluation crucial for performance analysis. Advanced computer vision techniques now enable precise real-time tracking and assessment of pitches.
Gohar Asad +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Aging Hallmarks and Anti-aging Strategies: A Landscape of Research Advancement [PDF]
, 2023 Aging is a dynamic, time-dependent process characterized by a gradual accumulation of cell damage. Continual functional decline in the intrinsic ability of living organisms to accurately regulate homeostasis leads to increased susceptibility and ...
Janet, Sasso +3 more
core +1 more source
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2009 Our anti-aging center (AAC) began providing health check-up services to local citizens in western Japan in February 2006, with the mission of promoting 'successful' aging through the employment of anti-aging check-ups, termed 'anti-aging dock' in Japan, using evidence-based 'anti-aging dock' strategies designed to diagnose atherosclerosis based on ...
openaire +4 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Fabrication of a Pneumatic Microparticle Concentrator
Micromachines, 2019 We developed a microfluidic platform employing (normally open) pneumatic valves for particle concentration. The device features a three-dimensional network with a curved fluidic channel and three pneumatic valves (a sieve valve (Vs) that concentrates ...
Jun Ho Jang, Ok Chan Jeong
doaj +1 more source
Effects of synbiotic supplement on LPS level in Thai smokers: A preliminary study
Asian Journal of Medical Sciences, 2020 Background: The impacts of smoking on the intestinal microbiome piece and arranged assortment have been appeared in different arranged controlled and observational clinical trials in individuals.
Parama Pratummas +6 more
doaj +1 more source
Embryonic anti-aging niche [PDF]
Aging, 2011 Although functional organ stem cells persist in the old, tissue damage invariably overwhelms tissue repair, ultimately causing the demise of an organism. The poor performance of stem cells in an aged organ, such as skeletal muscle, is caused by the changes in regulatory pathways such as Notch, MAPK and TGF-β, where old differentiated tissue actually ...
Conboy, Irina M +2 more
openaire +3 more sources