Results 41 to 50 of about 2,202,587 (262)

The effect of synbiotics supplement on alcohol use disorders identification test and biochemical parameters, gamma glutamyl transferase, lipopolysaccharide and immunoglobulin a levels, in high risk alcoholics

Asian Journal of Medical Sciences, 2020
Background: Alcohol consumption does not result in dependence or abuse among most people. Nevertheless, a significant group of the population as a whole unavoidably is troubled by chronic alcoholism.Alcohol is involved in a number of diseases, disorders,
Vachrintr Sirisapsombat , Parama Pratummas, Phuttharaksa Phucharoen, Thamthiwat Nararatwanchai , Chaiyavat Chaiyasut, Sasithorn Sirilun , Phakkharawat Sittiprapaporn   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Interleukin‐36α as a potential biomarker for renal tubular damage induced by dietary phosphate load

FEBS Open Bio, 2020
Excessive intake of phosphate has been known to induce renal tubular damage and interstitial inflammation, leading to acute kidney injury or chronic kidney disease in rodents and humans.
Yoshitaka Hirano, Hiroshi Kurosu, Kazuhiro Shiizaki, Yoshitaka Iwazu, Shuichi Tsuruoka, Makoto Kuro‐o   +5 more
doaj   +1 more source

A Vital Sign Analysis System Based on Algorithm Block Broker for Interoperability between Algorithm Development Tools

Applied Sciences, 2021
With the recent development of artificial intelligence and data mining technology, various and intelligent vital sign analysis technologies have been developed. Vital sign analysis algorithms and technologies are primarily developed using MATLAB and open
Moon-Il Joo, Hee-Cheol Kim
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Standardized low-resolution electromagnetic tomography of preattentive auditory discrimination in accumulative drinker

Asian Journal of Medical Sciences, 2020
Background: The present study proposes a task-dependent hypothesis in which the phonological units of segmental (e.g., consonant and vowel) and suprasegmental (e.g., prosodic) are processed in discrete asymmetry of the human brain.
Phakkharawat Sittiprapaporn
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Evaluation of the effectiveness of new health-improving devices Biotron EKOM in studies on mice and nematodes Caenorhabditis elegans

Российский журнал гериатрической медицины
The results of studying the effect of EKOM Family Biotrons on the life span of BALB/C mice and Caenorhabditis elegans nematodes are presented. The concentrated biological action of Biotron was found to increase the average and maximum lifespan of these ...
L. Yu. Prokhorov, E. V. Komrakov
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Deep learning-based anomaly detection using one-dimensional convolutional neural networks (1D CNN) in machine centers (MCT) and computer numerical control (CNC) machines [PDF]

PeerJ Computer Science
Computer numerical control (CNC) and machine center (MCT) machines are mechanical devices that manipulate different tools using computer programming as inputs.
Ali Athar, Md Ariful Islam Mozumder, Abdullah, Sikandar Ali, Hee-Cheol Kim   +4 more
doaj   +2 more sources