Results 81 to 90 of about 12,566,256 (291)

Fabrication of a Pneumatic Microparticle Concentrator

open access: yesMicromachines, 2019
We developed a microfluidic platform employing (normally open) pneumatic valves for particle concentration. The device features a three-dimensional network with a curved fluidic channel and three pneumatic valves (a sieve valve (Vs) that concentrates ...
Jun Ho Jang, Ok Chan Jeong
doaj   +1 more source

The effects for inflammatory responses by CPP with different colloidal properties in hemodialysis patients

open access: yesScientific Reports, 2022
Calciprotein particles (CPPs) are colloids composed of solid-phase calcium-phosphate and serum protein fetuin-A. CPPs form a polydispersed system with different particle size and density.
Hideyuki Mukai   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Embryonic anti-aging niche [PDF]

open access: yesAging, 2011
Although functional organ stem cells persist in the old, tissue damage invariably overwhelms tissue repair, ultimately causing the demise of an organism. The poor performance of stem cells in an aged organ, such as skeletal muscle, is caused by the changes in regulatory pathways such as Notch, MAPK and TGF-β, where old differentiated tissue actually ...
Conboy, Irina M   +2 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Enhancing Nuclei Segmentation in Histopathology Images via Quantitative to Qualitative Transitions in Supervised and Weakly Supervised Deep-Learning Approaches

open access: yesIEEE Access
Segmentation of nuclei in histopathology images stained with Hematoxylin and Eosin is essential for accurate disease diagnosis and tissue characterization.
Ijaz Muhammad Umer   +3 more
doaj   +1 more source

Interleukin‐36α as a potential biomarker for renal tubular damage induced by dietary phosphate load

open access: yesFEBS Open Bio, 2020
Excessive intake of phosphate has been known to induce renal tubular damage and interstitial inflammation, leading to acute kidney injury or chronic kidney disease in rodents and humans.
Yoshitaka Hirano   +5 more
doaj   +1 more source

Standardized low-resolution electromagnetic tomography of preattentive auditory discrimination in accumulative drinker

open access: yesAsian Journal of Medical Sciences, 2020
Background: The present study proposes a task-dependent hypothesis in which the phonological units of segmental (e.g., consonant and vowel) and suprasegmental (e.g., prosodic) are processed in discrete asymmetry of the human brain.
Phakkharawat Sittiprapaporn
doaj   +1 more source

Skin anti-aging strategies [PDF]

open access: yesDermato-Endocrinology, 2012
Skin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extrinsic factors. Because of the fact that skin health and beauty is considered one of the principal factors representing overall "well-being" and the perception of "health" in humans, several anti-aging strategies have been developed ...
Ganceviciene, Ruta   +4 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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