Results 161 to 170 of about 12,264,289 (383)

Anti-müllerian hormone (AMH) trajectories in reproductive aged african-american women: findings from the study of ovarian aging and reserve (SOAR) [PDF]

, 2019
Emma Giuliani, Anca Tilea, Veronica J. Berrocal, Mercedes R. Carnethon, Lia A. Bernardi, Lisa M. Neff, Erica E. Marsh   +6 more
openalex   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Market review of anti-age cosmetic products and the role of hyaluronic acid in skin redermalization processes

, 2020
Bogdan Putyatin, Ekaterina Kunitsіa, Irina Levchuk, Evgeny Gladukh   +3 more
openalex   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Karakterisasi Sediaan Topikal Anti Aging dari Kombinasi Ekstrak Pegagan dan Kulit Buah Manggis [PDF]

, 2016
CHARACTERIZATION OF ANTI AGING TOPICAL PREPARATION FROM COMBINATION OF CENTELLA ASIATICA AND MANGOSTEENS PEEL EXTRACT. Gotu kola contain triterpenoid active agent that has activity as wound healing and asiaticoside which can repair and strengthen skin ...
Meliana, Y. (Yenny), Septiyanti, M. (Melati)   +1 more
core  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Metadichol; An Agonist that Expresses the Anti-aging gene Klotho in Various Cell Lines

, 2023
Palayakotai Raghavan
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

IoMT and Blockchain Synergy: A Novel Approach to Health Data Validation and Storage

IEEE Access
The increasing adoption of Internet of Medical Things (IoMT) devices is revolutionizing healthcare, facilitating enhanced remote patient monitoring and data-driven clinical decision-making.
Abbas Syed Muhammad Ali, Sikandar Ali, Khan Ziaullah, Moon-Il Joo, Hee-Cheol Kim   +4 more
doaj   +1 more source