Results 181 to 190 of about 12,264,289 (383)

Effects of Cultivation Conditions for Apples on Growth Rates of Fruit Fly Larvae and Contents of Phenolics [PDF]

open access: yes, 2003
Apples were grown with 3 different alleyway groundcover management strategies, providing a wide range of nutrient availabilities to the trees, spanning the ranges normally found in both conventional and organic orchards.
Brandt, Kirsten   +3 more
core  

Metabolomics and Gut Microbiota in Elderly Patients with Diabetic Peripheral Neuropathy and Sarcopenia

open access: yesDiabetes, Metabolic Syndrome and Obesity
Xue Wang,1– 3 Fei Yu,1– 3 Qian Cai,1– 3 Baoying Li,2,4 Xiaoli Li,5 Chunli Fu,1– 3 Xin Yu,1– 3 Wenbin Yin,1– 3 Shudong Zeng,1– 3 Haiqing Gao,1– 3 Mei Cheng1– 3 1Department of Geriatric Medicine & Laboratory of Gerontology and Anti-Aging Research, Qilu
Wang X   +10 more
doaj  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Anti-Inflammatory and Vasorelaxant Effects Induced by an Aqueous Aged Black Garlic Extract Supplemented with Vitamins D, C, and B12 on Cardiovascular System [PDF]

open access: gold, 2023
Lucia Recinella   +16 more
openalex   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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