Results 11 to 20 of about 528,186 (197)

Acanthamoeba and bacteria produce antimicrobials to target their counterpart [PDF]

Parasites & Vectors, 2014
Background In the microbial ecosystem, microbes compete for space and nutrients. Consequently, some have developed the ability to kill or inhibit the growth of other competing microbes by producing antimicrobial substances.
Junaid Iqbal, Ruqaiyyah Siddiqui, Naveed Ahmed Khan   +2 more
doaj   +3 more sources

Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations. [PDF]

PLoS ONE, 2017
The widespread introduction of artemisinin-based combination therapy has contributed to recent reductions in malaria mortality. Combination therapies have a range of advantages, including synergism, toxicity reduction, and delaying the onset of ...
Holly Matthews, Jon Deakin, May Rajab, Maryam Idris-Usman, Niroshini J Nirmalan   +4 more
doaj   +5 more sources

Imidazothiazole Derivatives Exhibited Potent Effects against Brain-Eating Amoebae

Antibiotics, 2022
Naegleria fowleri (N. fowleri) is a free-living, unicellular, opportunistic protist responsible for the fatal central nervous system infection, primary amoebic meningoencephalitis (PAM).
Ruqaiyyah Siddiqui, Mohammed I. El-Gamal, Anania Boghossian, Balsam Qubais Saeed, Chang-Hyun Oh, Mohammed S. Abdel-Maksoud, Ahmad M. Alharbi, Hasan Alfahemi, Naveed Ahmed Khan   +8 more
doaj   +2 more sources

Silver(I)-NHC Complexes as Dual-Action Agents Against Pathogenic <i>Acanthamoeba</i> Trophozoites: Anti-Amoebic and Anti-Adhesion Activities. [PDF]

Int J Mol Sci
A series of six silver(I) complexes, namely bromo(1-benzyl-3-cinnamyl-benzimidazol-2-ylidene)silver (I) (1a), bromo[1-(4-methylbenzyl)-3-cinnamyl-benzimidazol-2-yliden]silver(I) (1b), bromo[1-(3-methoxylbenzyl)-3-cinnamyl-benzimidazol-2-yliden]silver(I) (
Hkiri S, Şahin N, Akın-Polat Z, Üstün E, Ly BMT, Özdemir İ, Sémeril D.   +6 more
europepmc   +2 more sources

Scientific basis for the therapeutic use of Cymbopogon citratus, stapf (Lemon grass)

Journal of Advanced Pharmaceutical Technology & Research, 2011
Cymbopogon citratus, Stapf (Lemon grass) is a widely used herb in tropical countries, especially in Southeast Asia. The essential oil of the plant is used in aromatherapy.
Gagan Shah, Richa Shri, Vivek Panchal, Narender Sharma, Bharpur Singh, A S Mann   +5 more
doaj   +2 more sources

Effects of Shape and Size of Cobalt Phosphate Nanoparticles against Acanthamoeba castellanii

Pathogens, 2019
T4 genotype Acanthamoeba are opportunistic pathogens that cause two types of infections, including vision-threatening Acanthamoeba keratitis (AK) and a fatal brain infection known as granulomatous amoebic encephalitis (GAE).
Ayaz Anwar, Leong Chi Fung, Areeba Anwar, Priyanka Jagadish, Arshid Numan, Mohammad Khalid, Syed Shahabuddin, Ruqaiyyah Siddiqui, Naveed Ahmed Khan   +8 more
doaj   +2 more sources

Cyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba <i>Balamuthia mandrillaris</i>. [PDF]

J Nat Prod
Balamuthia mandrillaris is a pathogenic free-living amoeba (pFLA) that can cause infection of the central nervous system (CNS), called Balamuthia amoebic encephalitis (BAE), as well as cutaneous and systemic diseases.
Lu C, Nelson S, Coy G, Neumann C, Parkinson EI, Rice CA.   +5 more
europepmc   +2 more sources

The effects of phosphanegold(I) thiolates on the biological properties of Acanthamoeba castellanii belonging to the T4 genotype [PDF]

Journal of Negative Results in Biomedicine, 2017
BackgroundGold compounds have shown promise in the treatment of non-communicable diseases such as rheumatoid arthritis and cancer, and are considered of value as anti-microbial agents against Gram-negative and Gram-positive bacteria, and have anti ...
R. Siddiqui, Farhat Abjani, Chien Ing Yeo, E. Tiekink, N. Khan   +4 more
semanticscholar   +2 more sources

Entamoeba histolytica-induced NETs are highly cytotoxic on hepatic and colonic cells due to serine proteases and myeloperoxidase activities [PDF]

Frontiers in Immunology
During intestinal and liver invasion by the protozoan parasite Entamoeba histolytica, extensive tissue destruction linked to large neutrophil infiltrates is observed.
Fabian Jorge-Rosas, César Díaz-Godínez, Samuel García-Aguirre, Santiago Martínez-Calvillo, Julio César Carrero   +4 more
doaj   +2 more sources

Anti-amoebic activity of a series of benzofuran/benzothiophene derivatives against Acanthamoeba castellanii belonging to the T4 genotype.

Journal of Applied Microbiology, 2022
AIMS To determine the anti-amoebic activity of benzofuran/benzothiophene-possessing compounds against Acanthamoeba castellanii of the T4 genotype. METHOD AND RESULTS A series of benzofuran/benzothiophene-possessing compounds were tested for their anti ...
N. Akbar, M. El‐Gamal, Seyed-Omar Zaraei, B. Saeed, N. Khan, R. Siddiqui   +5 more
semanticscholar   +1 more source