Results 191 to 200 of about 294,275 (335)

Piracetam as Neuroprotective, Anticonvulsant, and Anti-Anxiety Agent: An In Vivo Study on Ptz Epileptic Rats

openalex   +1 more source

The TAAR1 Agonist PCC0105004 Regulates Amygdala Synaptic Plasticity to Alleviate Anxiety-Like Behaviors in Rats. [PDF]

Pharmacol Res Perspect
Zhang Y, Zhang W, Yu L, Shi Y, Xu M, Wang H, Li C, Tian J.   +7 more
europepmc   +1 more source

Reduction of Rescue Treatment With Dupilumab for Chronic Rhinosinusitis With Nasal Polyps in Japan

The Laryngoscope, EarlyView.
This observational study examined the impact of add‐on dupilumab treatment on the use of rescue therapy in Japanese individuals with chronic rhinosinusitis with nasal polyps (CRSwNPs) using data from a large hospital‐based administrative claims database.
Mamoru Yoshikawa, Mitsuhiro Okano, Makiko Takeuchi, Yoshinori Sunaga, Mami Orimo, Masato Ishida   +5 more
wiley   +1 more source

Terrorism, Security, and the Threat of Counterterrorism [PDF]

, 2007
Wolfendale, Jessica
core  

NLX‐112 Randomized Phase 2A Trial: Safety, Tolerability, Anti‐Dyskinetic, and Anti‐Parkinsonian Efficacy

Movement Disorders, EarlyView.
Abstract Background Levodopa‐induced dyskinesia (LID) in Parkinson's disease (PD) is associated with ‘false neurotransmitter’ release of dopamine from serotonin (5‐HT) neurons. NLX‐112 is a first‐in‐class, highly selective 5‐HT1A receptor agonist which counteracts LIDs in experimental PD models.
Per Svenningsson, Per Odin, Filip Bergquist, Karin Wirdefeldt, Dag Nyholm, Mattias Andréasson, Ioanna Markaki, Anders C. Johansson, Måns Jergil, Christopher Jankosky, Mark A. Varney, Fabienne Herbrecht, Steven A. Johnson, Adrian Newman‐Tancredi   +13 more
wiley   +1 more source

Mushrooms, Microdosing, and Mental Illness: The Effect of Psilocybin on Neurotransmitters, Neuroinflammation, and Neuroplasticity. [PDF]

Neuropsychiatr Dis Treat
Kinderlehrer DA.
europepmc   +1 more source

Repeat Expansions with Small TTTCA Insertions in MARCHF6 Cause Familial Myoclonus without Epilepsy

Movement Disorders, EarlyView.
Abstract Background Familial adult myoclonus epilepsy (FAME) is a rare autosomal dominant disorder caused by the same intronic TTTTA/TTTCA repeat expansion in seven distinct genes. TTTTA‐only expansions are benign, whereas those containing TTTCA insertions are pathogenic.
Theresa Kühnel, Elsa Leitão, Renate Lunzer, Fabian Kilpert, Sabine Kaya, Claudia Del Gamba, Kelly Astudillo, Steven Frucht, Marion Simonetta‐Moreau, Eric Bieth, Iris Unterberger, Giulietta Maria Riboldi, Christel Depienne   +12 more
wiley   +1 more source

Interrupting the conversation: Donald MacKinnon, wartime tutor of Anscombe, Midgley, Murdoch and Foot

Journal of Philosophy of Education, Volume 56, Issue 6, Page 838-850, December 2022., 2022
Abstract Elizabeth Anscombe, Mary Midgley, Iris Murdoch and Philippa Foot all studied at Oxford University during the Second World War. One of their wartime tutors was Donald MacKinnon. This paper gives a broad overview of MacKinnon's philosophical outlook as it was developing at this time. Four talks from between 1938 and 1941—‘And the Son of Man That
Clare Mac Cumhaill, Rachael Wiseman
wiley   +1 more source

Involvement of the GABAergic and the serotonergic systems in the anxiolytic effects expressed by the nitric oxide (NO) donor sodium nitroprusside (SNP) in the male rat. [PDF]

Psychopharmacology (Berl)
Parlantza MA, Pitsikas N.
europepmc   +1 more source

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

Medicinal Research Reviews, EarlyView.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni, Giulia Galli, Clelia Dallanoce, Marco De Amici, Pau Gorostiza, Carlo Matera   +5 more
wiley   +1 more source