Results 201 to 210 of about 572,169 (326)

Personality Traits in Fibromyalgia: Aggravators and Attenuators of Clinical Symptoms and Medication Use. [PDF]

Behav Neurol
Santiago D, Montoro CI, Davydov DM, Reyes Del Paso GA.   +3 more
europepmc   +1 more source

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

Movement Disorders Clinical Practice, EarlyView.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori, Yohei Mukai, Noriko Nishikawa, Kazuko Hasegawa, Masahiko Tomiyama, Yasuyoshi Kimura, Yoshio Tsuboi, Ryosuke Takahashi, Ryota Nakamura, Yuishin Izumi, Hirohisa Watanabe, Morinobu Seki, Kenji Sekiguchi, Shohei Tateishi, Yusaku Matsushita, Yusaku Nakamura   +15 more
wiley   +1 more source

Ozone Treatment in the Management of Chemotherapy-Induced Peripheral Neuropathy: A Review of Rationale and Research Directions. [PDF]

Cancers (Basel)
Clavo B, Cánovas-Molina A, Federico M, Martínez-Sánchez G, Benítez G, Galván S, Ramallo-Fariña Y, Fabelo H, Cazorla-Rivero S, Lago-Moreno E, Antonilli C, Díaz-Garrido JA, Jorge IJ, Marrero-Callico G, Rodríguez-Abreu D, Rodríguez-Esparragón F.   +15 more
europepmc   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Zebrafish models for studying central nervous system effects of Ayurvedic medicinal plants. [PDF]

J Ayurveda Integr Med
Chakraborty P, Pal S, Galstyan DS, Petersen EV, Amstislavskaya TG, Kolesnikova TO, de Abreu MS, Kalueff AV.   +7 more
europepmc   +1 more source

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

Molecular Nutrition &Food Research, EarlyView.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina, Victor Nehmi Filho, Jéssica Alves de Freitas, Lucas Augusto Moysés Franco, Roberta Cristina Martins, Joyce Vanessa Fonseca, José Antônio Orellana Turri, Mariana Tedesco Hufnagel, Daniel Pecoraro Demarque, Bruna Fernanda Rio Branco da Silva, Arianne Fagotti Gusmão, Eloísa Helena Ribeiro Olivieri, Erica de Souza, Esther Alves de Souza, José Pinhata Otoch, Ana Flávia Marçal Pessoa   +15 more
wiley   +1 more source

Anti-Anxiety Effects of Essential Oil Microemulsion in Chronic Unpredictable Mild Stress-Induced Rats: Preparation, Characterization, and Mechanisms. [PDF]

Molecules
Tang W, Jiang P, Hu K, Mei D, Jiao Q, Li Y, Deng Y, Wang J, Gao R, Chen X, Yu J.   +10 more
europepmc   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
wiley   +1 more source

Breaking the diabetes-depression cycle: Exploring shared mechanisms, neuroinflammation, and emerging interventions for metabolic-mood comorbidities. [PDF]

World J Diabetes
Luo C, Yu XM, Zeng MQ, Duan CZ, Xu SY, Zhu CY, Zheng ZG, Sun D, Fang J, He DJ.   +9 more
europepmc   +1 more source

One‐Pot Gram‐Scale Synthesis of Cynandione A and Detailed Mechanistic Insights into its Regioselectivity

ChemistryOpen, EarlyView.
An improved one‐pot, gram‐scale synthesis of cynandione A, a key natural product from Cynanchi wilfordii Radix with diverse biological activities, has been developed. DFT calculations clarified the regioselectivity of the arylation step in the benzoquinone, revealing that the C3 position of the nucleophile is highly favored due to both kinetic and ...
Jun Sung Kang, Jin Yi Jung, Chan Jae Cho, Seoungwoo Kang, Yeonjoon Kim, Jae Hyun Kim   +5 more
wiley   +1 more source