Results 221 to 230 of about 384,866 (306)
The road to tranquility: The search for selective anti‐anxiety agents
Synapse, 1995 AbstractThe earliest treatments of anxiety included cathartics and emetics, which were used to remove the excess of black bile (hence our word melancholia) thought to be responsible for the patient's demeanor. By the 1700s, physicians were prescribing drugs that are more selective for the CNS, chiefly opium and strengthening tonics.
J. Worth Estes
semanticscholar +4 more sources
Chapter 1. Antipsychotic and Anti-anxiety Agents
, 1970 Publisher Summary This chapter discusses the results of studies focusing on antipsychotic and anti-anxiety agents. A double blind controlled study showed an approximately 10% better response in schizophrenic patients with droperidol than with haloperidol.
R. Ian Fryer
semanticscholar +3 more sources
Chapter 32 Hypnotics and anti-anxiety agents
, 1997 Summary Depression of the central nervous system can be achieved with a wide variety of chemical agents. Depending on dose, increasing levels of effect consisting of (a) anti-anxiety effects, (b) sedation, (c) sleep, (d) anesthesia, and (e) coma (with risk of a fatal outcome) may be produced. Frequently the same agent may be used at a greater dose to
Arthur Raines
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Behavioural Validation of a Light/Dark Choice Procedure for Testing Anti-Anxiety Agents
Behavioural Processes, 1989 In order to teat the behavioural value of a two-chambered light/dark choice procedure used for pharmacological studies, we investigated the effects of several internal and external factors on two variables: the time spent by mice in the lit box (TLB) and the number of transitions between the lit box and the dark one.
R, Misslin, C, Belzung, E, Vogel
semanticscholar +4 more sources
Chapter 1. Antipsychotic and Antianxiety Agents
, 1972 Publisher Summary This chapter presents results of studies that analyze antipsychotic and antianxiety agents. The use of long-acting fluphenazine in the management of schizophrenia and its comparison with conventional therapy was reviewed. Studies of other 6-6-6 tricyclics included several new phenothiaaine derivatives. A diazabicyclononane analog of
Charles L. Zirkle, Carl Kaiser
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Chapter 1. Anti-Anxiety Agents and Sedative-Hypnotics
, 1985 Publisher Summary In this chapter, the pharmacological actions of different anti-anxiety agents and sedative-aypnotics have been discussed with current references. Current evidence indicates that most anxiolytic and sedative-hypnotic drugs exert their pharmacological actions by binding to discrete neuronal recognition sites, consisting of ...
Barbara Petrack, Naokata Yokoyama
semanticscholar +3 more sources
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Spiro Benzodiazepine Substituted Fluorocoumarins as Potent Anti-Anxiety Agents
Russian Journal of Bioorganic Chemistry, 20211,5-Benzodiazepines are one of the important class of tranquilizers. The fusion of heterocyclic systems like coumarins and indolines with the benzodiazepine seems quite encouraging for the synthesis of derivatives with enhanced anti-anxiety property. The benzodiazepine derivatives containing fluorine were synthesized and studied for their anti-anxiety ...
Dayanand Patagar +6 more
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Prediction of Response to Anti-Anxiety Agents
, 1979 C. HALLSTRÖM, M. LADER
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Anti-anxiety agents: a pharmacoepidemiological review
Human Psychopharmacology: Clinical and Experimental, 1999The purpose of this review is to broaden the base for informed policy and to identify research issues to improve the utility of anti-anxiety agents. Data quality is discussed and the prevalence of morbid anxiety and the exposure to treatment with, and abuse of, anti-anxiety agents in different populations is presented.
C. Allgulander
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A simple and reliable conflict procedure for testing anti-anxiety agents
Psychopharmacologia, 1971The effects of three benzodiazepines (chlordiazepoxide, diazepam, and oxazepam), meprobamate, pentobarbital, d-amphetamine sulfate, magnesium pemoline, and scopolamine hydrobromide were studied with a simple conflict procedure in which thirsty naive rats were periodically administered shocks for licking water.
J R, Vogel, B, Beer, D E, Clody
openaire +3 more sources