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Anti-anxiety agents: duration of use and characteristics of users in the U.S.A.
A national survey of psychotherapeutic drug use was carried out in the U.S.A. in 1979. Data were obtained from a probability sample (n = 3161) of adults in the general population, using a clinically-oriented interview lasting an average of 90 minutes.
Glen D. Mellinger+2 more
semanticscholar +5 more sources
A simple and reliable conflict procedure for testing anti-anxiety agents
The effects of three benzodiazepines (chlordiazepoxide, diazepam, and oxazepam), meprobamate, pentobarbital, d-amphetamine sulfate, magnesium pemoline, and scopolamine hydrobromide were studied with a simple conflict procedure in which thirsty naive rats were periodically administered shocks for licking water.
John R. Vogel+2 more
semanticscholar +5 more sources
Chapter 1. Antipsychotic and Anti-anxiety Agents
Publisher Summary This chapter presents results of studies that analyze antipsychotic and antianxiety agents. The use of long-acting fluphenazine in the management of schizophrenia and its comparison with conventional therapy was reviewed. Studies of other 6-6-6 tricyclics included several new phenothiaaine derivatives. A diazabicyclononane analog of
Charles L. Zirkle, Carl Kaiser
semanticscholar +4 more sources
Chapter 1. Antipsychotic and Anti-anxiety Agents
Publisher Summary This chapter discusses results of studies focusing on antipsychotic and antianxiety agents. Studies revealed that medazepam alleviates anxiety and tension in children and adults with minimal sedative side effect and without impairment of working capacity or normal alertness.
Irwin J. Pachter, Alan A. Rubin
semanticscholar +4 more sources
Chapter 32 Hypnotics and anti-anxiety agents
Summary Depression of the central nervous system can be achieved with a wide variety of chemical agents. Depending on dose, increasing levels of effect consisting of (a) anti-anxiety effects, (b) sedation, (c) sleep, (d) anesthesia, and (e) coma (with risk of a fatal outcome) may be produced. Frequently the same agent may be used at a greater dose to
Arthur Raines
semanticscholar +4 more sources
Adjunctive Use of Anti-Anxiety Agents
Paul E. Feldman
semanticscholar +5 more sources
Anti-anxiety agents: a pharmacoepidemiological review [PDF]
The purpose of this review is to broaden the base for informed policy and to identify research issues to improve the utility of anti-anxiety agents. Data quality is discussed and the prevalence of morbid anxiety and the exposure to treatment with, and abuse of, anti-anxiety agents in different populations is presented.
C. Allgulander
openaire +2 more sources
Chapter 1. Antipsychotic and Anti-anxiety Agents
Publisher Summary This chapter discusses the results of studies focusing on antipsychotic and anti-anxiety agents. A double blind controlled study showed an approximately 10% better response in schizophrenic patients with droperidol than with haloperidol.
R. Ian Fryer
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Animal models for the study of anti-anxiety agents: A review
Neuroscience & Biobehavioral Reviews, 1985Animal models for the study of anxiolytic agents are reviewed and evaluated according to pharmacological and behavioral criteria. Although there are important exceptions, in general, most early animal models have not provided a reliable basis for identifying compounds with potential anxiolytic action, or for delineating the mechanisms of anxiolytic ...
D. Treit
openaire +3 more sources
Chapter 2. Anti-Anxiety Agents, Anticonvulsants and Sedative-Hypnotics
Publisher Summary This chapter describes the metabolic studies of Lorazepam in man and animals, Pinazepams in man, Diazepam in human kidney cortex microsomes and bile, and Nitrazepam in rabbit urine. N-desmethyldiazepam is a new human metabolite of chlorodiazepoxid, e.g Diazepam and its main active metabolite desmethyldiazepam, pass into the breast ...
William J. Houlihan, G. B. BENNETT
+5 more sources