Results 281 to 290 of about 592,213 (353)
Some of the next articles are maybe not open access.
Enhancement of 3H-diazepam binding by SQ 65,396: A novel anti-anxiety agent
SQ 65,396, a clinically active anti-anxiety agent, enhanced the binding of 3H-diazepam at 1.5 nM. This effect was due to an increase in the affinity for the ligand, without a change in the number of 3H-diazepam binding sites. This action of SQ 65,396 may mediate its anti-anxiety effects by affecting the action of an endogenous modulator of the ...
Bernard Beer +3 more
openalex +3 more sources
Chapter 2. Anti-Anxiety Agents, Anticonvulsants & Sedative-Hypnotics
Publisher Summary Studies on pharmacotherapy for anxiety continue to evolve along the dual paths of agents and actions. While benzodiazepines (BZs) continue to be the agents of choice for anxiolysis, new series of non-BZ compounds are emerging that may offer alternatives in the management of anxiety disorders.
Joseph P. Yevich +2 more
openalex +2 more sources
Chapter 2. Anti-Anxiety Agents, Anticonvulsants and Sedative-Hypnotics
Publisher Summary This chapter describes the metabolic studies of Lorazepam in man and animals, Pinazepams in man, Diazepam in human kidney cortex microsomes and bile, and Nitrazepam in rabbit urine. N-desmethyldiazepam is a new human metabolite of chlorodiazepoxid, e.g Diazepam and its main active metabolite desmethyldiazepam, pass into the breast ...
William J. Houlihan, G. B. BENNETT
openalex +2 more sources
Chapter 3. Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
Joel G. Berger, Louis C. Iorio
openalex +2 more sources
Medicinal chemistry, 2021
BACKGROUND Iminostilbene and 1,2,3-triazole ring containing compounds are considered as beneficial substrates in drug design. OBJECTIVES This study was aimed at the synthesis of novel series of iminostilbene linked 1,2,3- triazole pharmacophores (7c-n)
Kariyappa N. Ankali +3 more
semanticscholar +1 more source
BACKGROUND Iminostilbene and 1,2,3-triazole ring containing compounds are considered as beneficial substrates in drug design. OBJECTIVES This study was aimed at the synthesis of novel series of iminostilbene linked 1,2,3- triazole pharmacophores (7c-n)
Kariyappa N. Ankali +3 more
semanticscholar +1 more source
[Anti-emetic and anti-anxiety agents].
Jérôme Ouellet
openalex +2 more sources
Avicenna Journal of Phytomedicine, 2017
Objectives: The extract of Lippia citriodora and its main component, verbascoside, are known for their hypnotic effects in traditional medicine. In this study, the anxiolytic and hypnotic effects of L.
B. Razavi, N. Zargarani, H. Hosseinzadeh
semanticscholar +1 more source
Objectives: The extract of Lippia citriodora and its main component, verbascoside, are known for their hypnotic effects in traditional medicine. In this study, the anxiolytic and hypnotic effects of L.
B. Razavi, N. Zargarani, H. Hosseinzadeh
semanticscholar +1 more source
Psychedelics as anti-inflammatory agents
International Review of Psychiatry, 2018Serotonin (5-hydroxytryptamine, 5-HT)2A receptor agonists have recently emerged as promising new treatment options for a variety of disorders. The recent success of these agonists, also known as psychedelics, like psilocybin for the treatment of anxiety,
Thomas W. Flanagan, C. Nichols
semanticscholar +1 more source

