Results 141 to 150 of about 326,497 (313)

Hormone Therapy Usage Is Associated With Adverse Cardiovascular Events in Prostate Cancer Patients of the All of Us Research Program Cohort

The Prostate, Volume 85, Issue 12, Page 1077-1086, September 2025.
ABSTRACT Background Hormone therapy (HT) has greatly improved overall survival for prostate cancer patients, but may also influence cardiovascular health in an already high‐risk population. Methods This retrospective cohort study examined participants in the All of Us Research Program with prostate cancer, had no prior history of adverse cardiovascular
Yuanchu J. Yang, Chenjie Zeng, Kerry R. Schaffer, Tam C. Tran, Peter J. Sauer, Lincoln A. Brown, Ben H. Park, Joshua C. Denny   +7 more
wiley   +1 more source

A Case of Ventricular Arrhythmia in a Patient With HER2-Positive Gastric Cancer Receiving Trastuzumab. [PDF]

Case Rep Gastrointest Med
Takahashi N, Fujii H, Iwasa T, Koizumi Y, Minagawa Y, Tono C.   +5 more
europepmc   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, Volume 89, Issue 5, Page 384-397, September 2025.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source

Prediction of Cardiac Arrhythmias in Cancer Patients Treated with Immune Checkpoint Inhibitors Using Electrocardiogram. [PDF]

Diagnostics (Basel)
Coskun A, Celebi Coskun E, Bilgehan Sahin A, Levent F, Coban E, Koca F, Sali S, Demir OF, Deligonul A, Tenekecioglu E, Cubukcu E, Vatansever Agca F, Evrensel T.   +12 more
europepmc   +1 more source

Combined inhibition of atrial‐specific potassium currents as a possible anti‐arrhythmic drug therapy: A match made in silico

The Journal of Physiology, EarlyView.
Vladimír Sobota
wiley   +1 more source

Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes

Annals of Human Genetics, Volume 89, Issue 5, Page 398-405, September 2025.
ABSTRACT Pharmacogenomics, the use of germline genomic data to guide prescription to improve effective and safer medication, holds promise as a clinical intervention. To date in most health systems, there has been limited uptake of pharmacogenomic testing confined to a few single drug–gene associations.
John Henry McDermott, Videha Sharma, Jessica Keen, William Gerard Newman   +3 more
wiley   +1 more source

Independent derivations of the axis of arrhythmia for predicting drug‐induced torsades de pointes

British Journal of Pharmacology, Volume 182, Issue 18, Page 4299-4313, September 2025.
Abstract Background and Purpose: Torsades de pointes is a potentially lethal ventricular arrhythmia that can be induced by many classes of drugs. The risk for a given drug depends upon the combination of cardiac ion channels that it targets. The axis of arrhythmia quantifies that risk. It is a conceptual line in the electrophysiology that describes the
Stewart Heitmann, Jamie I. Vandenberg, Adam P. Hill   +2 more
wiley   +1 more source

[Propafenone as an anti-arrhythmia agent].

Wiadomosci lekarskie (Warsaw, Poland : 1960), 1987
A, Tomaszewski, A, Kleinrok, M, Markiewicz   +2 more
openaire   +1 more source

The lack of evidence-based management in electrical storm: a scoping review. [PDF]

BMC Cardiovasc Disord
Motazedian P, Prosperi-Porta G, Mathieu ME, Beauregard N, Knoll W, Quinn N, Parlow S, Di Santo P, Abdel-Razek O, Jung R, Kolobaric N, Barbour W, Nelson D, Simard T, Jentzer JC, Mathew R, Wells GA, Ramirez FD, Hibbert B.   +18 more
europepmc   +1 more source

Dexrazoxane protects against doxorubicin‐induced cardiotoxicity in susceptible human living myocardial slices: A proof‐of‐concept study

British Journal of Pharmacology, Volume 182, Issue 18, Page 4262-4280, September 2025.
Abstract Background and Purpose The increasing number of cancer survivors has caused growing concern over chemotherapy‐induced cardiotoxicity. This study aimed to investigate a novel human model of cardiotoxicity and explore cardioprotection. Experimental Approach Living myocardial slices (LMS) were obtained from explanted end‐stage heart failure ...
Jort S. A. van der Geest, Ilse R. Kelters, Bauke Arends, Willem B. van Ham, Ernest Diez Benavente, Thirza A. Lapré, Petra van der Kraak, Pim van der Harst, Arco J. Teske, Andreas Dendorfer, M. Mostafa Mokhles, Pieter A. Doevendans, Teun P. de Boer, Linda W. van Laake, Joost P. G. Sluijter, Vasco Sampaio‐Pinto   +15 more
wiley   +1 more source