Baseline vs. on-treatment heart failure with preserved ejection fraction (HFpEF) in a real world cardio-oncology clinic: observational analysis of cancer therapy-related cardiovascular toxicity incidence and cancer treatment implications. [PDF]
von Kemp B +6 more
europepmc +1 more source
ABSTRACT Background and Aim: Obscure gastrointestinal bleeding (OGIB) is defined as bleeding of unknown origin after comprehensive upper, lower, and small‐bowel evaluations. However, the incidence and predictors of rebleeding after negative comprehensive gastrointestinal evaluation remain unclear.
Sachiyo Onishi +8 more
wiley +1 more source
Cardiovascular Implications of the Enhanced Games: Performance Enhancing Drugs in Competition and Recreation. [PDF]
Vecchiato M +10 more
europepmc +1 more source
ABSTRACT Adult patients with inherited metabolic diseases are often overlooked. Limited data on this population hinder adequate planning of their clinical and social care. In this retrospective, observational, cross‐sectional service evaluation study, we reviewed the electronic medical records of adult patients with inherited neurometabolic diseases ...
Boel Ernerdahl +2 more
wiley +1 more source
Synergistic antiarrhythmic mechanism of I<sub>Na-L</sub> and RyR2 blockade: normalization of pathological calcium cycling and CaMKII signaling. [PDF]
Ju M +7 more
europepmc +1 more source
Autophagy in MASLD: A Metabolic and Precision Medicine Perspective
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga +4 more
wiley +1 more source
Ultrasound-Guided Regional Anesthesia for Repeat Ventricular Arrhythmia Catheter Ablation: A Case Report. [PDF]
Farokhnia R +4 more
europepmc +1 more source
Inactivation of the Nrf2/Are pathway in AD leads to decreased antioxidant and anti‐inflammatory response and to the accumulation of beta‐amyloid (Aβ) plaques, resulting in cognitive failure. Treatment with Isoeugenol activates Nrf2, reversing these outcomes by promoting antioxidant response in neuronal cells (N2a) and by increasing the anti ...
Ana Silva +14 more
wiley +1 more source
The rapid integration of immune checkpoint inhibitors (ICIs) into standard oncology protocols has birthed a new frontier in clinical rheumatology: immune‐related adverse events (irAEs). By disrupting the programmed cell death‐1 (PD‐1)/PD‐L1 and cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) axes to restore antitumor T cell activity, these ...
Xizi Hu +3 more
wiley +1 more source
Case report: an underdiagnosed multifocal ectopic Purkinje-related premature contractions caused by SCN5A mutation. [PDF]
Cao W +9 more
europepmc +1 more source

