Results 161 to 170 of about 46,906 (308)

Frequently Underappreciated Considerations in Anti-arrhythmic Drug Therapy. [PDF]

J Innov Card Rhythm Manag
Reiffel JA.
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Population Modeling Approach for Human Cardiac Arrhythmia Risk Prediction. [PDF]

Circ Arrhythm Electrophysiol
Song Z, Sui F, Huang X, Liu MB, Gao W, Weiss JN, Qu Z.   +6 more
europepmc   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Ultrasound-Guided Regional Anesthesia for Repeat Ventricular Arrhythmia Catheter Ablation: A Case Report. [PDF]

Cureus
Farokhnia R, Sanchorawala A, Padakandla UB, Rao P, Ramamoorthy S.   +4 more
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

QT-related adverse events with ondansetron and olanzapine: a real-world FAERS analysis with implications for oncology anti-emetic practice. [PDF]

Front Pharmacol
Gandhi A, Parhizgar A, Bhise V.
europepmc   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Electrocardiographic manifestations and targeted management of cardiac complications in cardiac-involved DLBCL: a retrospective case series. [PDF]

Cardiooncology
Chuang JY, Chen KT, Lin J, Lim KH, Sung MT.   +4 more
europepmc   +1 more source

Cardiotoxicity associated with anticancer therapies for gynecological tumors. [PDF]

Front Cardiovasc Med
Yang L, Liao J, Li J, Wang Z.
europepmc   +1 more source