Results 181 to 190 of about 383,105 (350)

Pirtobrutinib in Chinese patients with relapsed or refractory B‐cell malignancies: A single‐arm, open‐label, phase 2, multicenter trial

International Journal of Cancer, Volume 156, Issue 11, Page 2158-2168, 1 June 2025.
What's new? Pirtobrutinib, a highly selective, noncovalent (reversible) Bruton tyrosine kinase inhibitor (BTKi), has shown promise in treating patients with B‐cell malignancies following treatment with covalent BTKis. However, potential geographic and ethnic differences in patient response to pirtobrutinib remain to be clarified.
Yanyan Liu, Ningjing Lin, Shuhua Yi, Huiqiang Huang, Ye Guo, Qingyuan Zhang, Haiyan Yang, Huilai Zhang, Liling Zhang, Ru Feng, Yijiao Qian, Jiankun Zhu, Yuqin Song, Jun Zhu   +13 more
wiley   +1 more source

Translationally controlled tumor protein interacts with connexin 43 and facilitates intercellular coupling between cardiomyocytes. [PDF]

Front Cell Dev Biol
Hu Y, Cai W, Hidaka Y, Hiraishi K, Cang J, Umemura M, Yokoyama U, Knollmann BC, Ishikawa Y, Fujita T.   +9 more
europepmc   +1 more source

Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED‐CARE): A protocol for a randomized clinical trial

Acta Anaesthesiologica Scandinavica, Volume 69, Issue 5, May 2025.
Abstract Background Sedation is often provided to resuscitated out‐of‐hospital cardiac arrest (OHCA) patients to tolerate post‐cardiac arrest care, including temperature management. However, the evidence of benefit or harm from routinely administered deep sedation after cardiac arrest is limited.
A. Ceric, J. Dankiewicz, J. Hästbacka, P. Young, V. H. Niemelä, F. Bass, M. B. Skrifvars, N. Hammond, M. Saxena, H. Levin, G. Lilja, M. Moseby‐Knappe, M. Tiainen, M. Reinikainen, J. Holgersson, C. B. Kamp, M. P. Wise, P. J. McGuigan, J. White, K. Sweet, T. R. Keeble, G. Glover, P. Hopkins, C. Remmington, J. M. Cole, N. Gorgoraptis, D. G. Pogson, P. Jackson, J. Düring, A. Lybeck, J. Johnsson, J. Unden, A. Lundin, J. Kåhlin, J. Grip, E. M. Lotman, L. Romundstad, P. Seidel, P. Stammet, T. Graf, A. Mengel, C. Leithner, J. Nee, P. Druwé, K. Ameloot, A. Nichol, M. Haenggi, M. P. Hilty, M. Iten, C. Schrag, M. Nafi, M. Joannidis, C. Robba, T. Pellis, J. Belohlavek, D. Rob, Y. M. Arabi, S. Buabbas, C. Yew Woon, A. Aneman, A. Stewart, M. Reade, C. Delcourt, A. Delaney, M. Ramanan, B. Venkatesh, L. Navarra, B. Crichton, A. Williams, D. Knight, J. Tirkkonen, T. Oksanen, T. Kaakinen, S. Bendel, H. Friberg, T. Cronberg, J. C. Jakobsen, N. Nielsen   +77 more
wiley   +1 more source

Role of Antiplatelets and Anticoagulation Therapies in Pregnancy. [PDF]

J Clin Med
Zachariah KA, Yuan S, DeSancho MT, Landres IV, Singh HS.   +4 more
europepmc   +1 more source

Natural trajectory subclasses of cognitive impairment in breast cancer patients experiencing insomnia

Cancer, Volume 131, Issue 8, 15 April 2025.
Abstract Background Cancer‐related cognitive impairment (CRCI) has traditionally been assessed in a dichotomous manner. Identifying subclasses of CRCI and novel biomarkers can improve the accuracy of identifying patients most at risk for CRCI. Methods A total of 139 breast cancer patients undergoing chemotherapy completed neurocognitive batteries over ...
Oxana Palesh, Sarah E. Braun, Tina Truong, Susan Hong, Masato Mitsuhashi, Ruth Nyagaka, Susanne Lee, Adithi Gandhi, Alexa De La Torre Schutz, Shelli R. Kesler   +9 more
wiley   +1 more source

Myocarditis: Diagnostic Modalities and Treatment Options. [PDF]

Cureus
Thilakaratne D, Bista R, Zenker M, Kaza R, Raissi S, Paul T.   +5 more
europepmc   +1 more source

Bioactive Inorganic Materials for Innervated Multi‐Tissue Regeneration

Advanced Science, Volume 12, Issue 13, April 3, 2025.
This review comprehensively summarizes the recent advancements of inorganic biomaterials for innervated multi‐tissue regeneration. It emphasizes the design principles of inorganic‐based material composites and their application in functional regeneration of nerves, bone, muscles, skin, and cavernous tissues.
Hongjian Zhang, Ziyi Zhao, Chengtie Wu
wiley   +1 more source

Arrhythmic Mitral Valve Prolapse: Late Correct Diagnosis. [PDF]

JACC Case Rep
Mirshafiee S, Aamaraee Z, Eftekhari M, Mollazadeh R.   +3 more
europepmc   +1 more source

Effects of Midazolam and Dexmedetomidine on Cognitive Dysfunction Following Open‐Heart Surgery: A Comprehensive Review

Brain and Behavior, Volume 15, Issue 4, April 2025.
ABSTRACT Purpose Patients undergoing open‐heart surgery often face significant challenges in postoperative cognitive dysfunction (POCD). There has been growing interest in understanding how anesthesia medications, such as dexmedetomidine (DEX) and midazolam, impact cognitive function in these patients.
Masoomeh Tabari, Ali Moradi, Golbon Asalforoush Rezaieh, Malihe Aghasizadeh   +3 more
wiley   +1 more source

Dauricine: Review of Pharmacological Activity. [PDF]

Drug Des Devel Ther
Chen KQ, Wang SZ, Lei HB, Liu X.
europepmc   +1 more source