Results 191 to 200 of about 46,906 (308)

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source

Incremental benefits of catheter ablation in patients with structural heart disease undergoing implantable cardioverter-defibrillator therapy for ventricular arrhythmias: A PRISMA compliant systematic review and meta analysis. [PDF]

Medicine (Baltimore)
Amir M, Hassan A, Ali EF, Noor M, Nazir A, Kamran M, Rizwan A, Fahim MA, Usman M, Awais MN, Waleed M, Tahir MU, Khan MH, Haroon A.   +13 more
europepmc   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

The Cardiovascular Effects of Inflammatory Bowel Disease Therapy with Biologics and Small Molecules: A Comprehensive Review. [PDF]

J Clin Med
Mastoridou EM, Fousekis FS, Sakellariou XM, Mpakogiannis K, Nikas DN, Michalis LK, Katsanos KH, Milionis H.   +7 more
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Epicardial Adipose Tissue as a Cardiometabolic Target in Atrial Fibrillation: Implications for Ablation Strategies and Emerging Metabolic Therapies. [PDF]

Med Sci (Basel)
Cacciapuoti F.
europepmc   +1 more source

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source

Refractory ventricular tachycardia storm with 42 ICD shocks in 24 h: A case report. [PDF]

Med Int (Lond)
Adrejiya P, Neshat N, Qamar AR, Suthar H, Orjioke N, Thandra A, Patel D.   +6 more
europepmc   +1 more source

[Anti-arrhythmia agents].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979
openaire   +1 more source

Practical compendium of antiarrhythmic drugs: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology. [PDF]

Europace
Merino JL, Tamargo J, Blomström-Lundqvist C, Boriani G, Crijns HJGM, Dobrev D, Goette A, Hohnloser SH, Naccarelli GV, Reiffel JA, Tfelt-Hansen J, Martínez-Cossiani M, Camm AJ, Almendral Garrote JM, Średniawa B, Kułakowski P, Savelieva I, Potpara T, Gorenek B, Zamorano JL.   +19 more
europepmc   +1 more source