Results 231 to 240 of about 355,535 (359)

Protein O‐GlcNAcylation in Health and Diseases

MedComm, Volume 6, Issue 12, December 2025.
We first introduced the beneficial effects of normal protein O‐GlcNAcylation on health, impacting biological processes such as gene expression, cell cycle progression, metabolism, and signal transduction. Next, we described the role of abnormal protein O‐GlcNAcylation in the development and progression of diseases, including neurodegenerative diseases,
Zhihong Ran, Chuanbao Chen, Jingfeng Ou, Guanyi Wu, Chao Yang, Xiaoyou Liu   +5 more
wiley   +1 more source

Atrial Fibrillation Recurrence Reduction: What Treatments Work Best Postablation? A Network Meta-Analysis. [PDF]

J Cardiovasc Electrophysiol
Jaroonpipatkul S, Sathapanasiri T, Ranjan R.   +2 more
europepmc   +1 more source

Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu, Xiao‐Mei Wu, Yan Hu, Xiao‐Lan Bian, Ya‐Qin Wang, Qiong‐Ni Zhu   +5 more
wiley   +1 more source

Cardiotoxicity Secondary to Accidental Tilmicosin (Micotil®300) Ingestion in a Young Shepherd: A Case Report. [PDF]

Am J Case Rep
Sheikh ZB, Alalawi BS, Alradaddi FM, Elbadri AY.   +3 more
europepmc   +1 more source

[Anti-arrhythmia agents and sudden death].

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1992
openaire   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, Volume 1, Issue 3, Page 322-358, December 2025.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

A Fulminant Case of Refractory Sarcoidosis Triggered by Infliximab-Neutralizing Antibodies. [PDF]

Cureus
Ibraheem M, Owda F, Mallah S, Saleem H, Nabhan A, Azar J.   +5 more
europepmc   +1 more source

Polymyxin B Induced Acute Diaphragmatic Paralysis: A Case Report Based on Therapeutic Drug Monitoring

Pharmacology Research &Perspectives, Volume 13, Issue 6, December 2025.
ABSTRACT Polymyxin B (PMB), a last‐resort antibiotic for multidrug‐resistant Gram‐negative infections, carries significant neurotoxicity risks that remain underrecognized in clinical practice. Here, we present a case of life‐threatening diaphragmatic paralysis induced by PMB in a patient with extensive neck and mediastinal infections caused by ...
Yunli Zhang, Xiaogang Tang, Yan Li, Xia Su, Xiaohong Zhong, Zhai Huang   +5 more
wiley   +1 more source

Neuromodulation of the Cardiac Autonomic Nervous System for Arrhythmia Treatment. [PDF]

Biomedicines
Wong B, Kuwabara Y, Salavatian S.
europepmc   +1 more source

[Classification of anti-arrhythmia agents and their characteristics].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991
openaire   +1 more source