Results 21 to 30 of about 326,497 (313)
Frontiers in Pharmacology, 2020 Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited, stressed-provoked ventricular arrhythmia. CPVT is treated by β-adrenergic receptor blockers, Na+ channel inhibitors, sympathetic denervation, or by implanting a defibrillator ...
Hanna Bueno-Levy +8 more
doaj +1 more source
Cells, 2022 Heat shock proteins (HSPs) are endogenous protective proteins and biomarkers of cell stress response, of which examples are HSP70, HSP60, HSP90, and small HSPs (HSPB).
Daiqi Liu +5 more
doaj +1 more source
Frontiers in Physiology, 2021 BackgroundCombined treatment with anthracyclines (e.g., doxorubicin; Dox) and trastuzumab (Trz), a humanized anti-human epidermal growth factor receptor 2 (HER2; ErbB2) antibody, in patients with HER2-positive cancer is limited by cardiotoxicity, as ...
Claudia Altomare +19 more
doaj +1 more source
Molecular Insights in Atrial Fibrillation Pathogenesis and Therapeutics: A Narrative Review
Diagnostics, 2021 The prevalence of atrial fibrillation (AF) is bound to increase globally in the following years, affecting the quality of life of millions of people, increasing mortality and morbidity, and beleaguering health care systems.
Konstantinos A. Papathanasiou +13 more
doaj +1 more source
Role of Pulmonary Vein in Atrial Fibrillation
Majalah Kardiologi Indonesia, 2013 Background. Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, occurring in1–2% of the general population and likely to increase in next 50 years.
Dian Andina Munawar, Yoga Yuniadi
doaj +1 more source
Symptomatic Myocardial Bridging Treated by Coronary Stenting
Majalah Kardiologi Indonesia, 2014 Background : Myocardial bridging is a congenital coronary anomaly with mostly benign course throughout life. However, several pathological clinical manifestations may accompany myocardial bridging, such as arrhythmia, angina, depressed left ventricular ...
Johan Winata +3 more
doaj +1 more source
Research Progress on Effects of Ginsenoside Rg2 and Rh1 on Nervous System and Related Mechanisms
Molecules, 2023 Neurological-related disorders are diseases that affect the body’s neurons or peripheral nerve tissue, such as Parkinson’s disease (PD) and Alzheimer’s disease (AD).
Silu Liu +5 more
doaj +1 more source
Pharmacologic prophylaxis for atrial fibrillation following cardiac surgery: a systematic review
Journal of Cardiothoracic Surgery, 2010 Atrial Fibrillation (AF) is the most common arrhythmia occurring after cardiac surgery. Its incidence varies depending on type of surgery. Postoperative AF may cause hemodynamic deterioration, predispose to stroke and increase mortality.
Baikoussis Nikolaos G +4 more
doaj +1 more source
A Case for Pharmacogenomics in Management of Cardiac Arrhythmias
Indian Pacing and Electrophysiology Journal, 2012 Disorders of the cardiac rhythm are quite prevalent in clinical practice. Though the variability in drug response between individuals has been extensively studied, this information has not been widely used in clinical practice.
Gaurav Kandoi +3 more
doaj +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source