Biologic Therapy in Severe Asthma: A Phenotype-Driven and Targeted Approach. [PDF]
D'Amato M +11 more
europepmc +1 more source
Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology +4 more
wiley +1 more source
Drugs Used in the Treatment of Viral Infections for the Prevention of Airway Remodeling in Asthma. [PDF]
Wieczfinska J, Pawliczak R.
europepmc +1 more source
ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu +7 more
wiley +1 more source
Thioredoxin-interacting protein as a crucial regulator in asthma exacerbation induced by copper oxide nanoparticles in a mouse model. [PDF]
Kim WI +10 more
europepmc +1 more source
The Impact of Environmental Pollution and Climate Change on Allergic Rhinitis and Lung Diseases
ABSTRACT Environmental pollution and climate change seriously affect human health, leading to the onset and exacerbation of chronic respiratory diseases, such as allergic rhinitis and lung diseases. Over the past several decades, increasing air pollution and environmental exposure owing to global urbanization, industrialization, and rapid economic ...
Xin‐Yan Liu +4 more
wiley +1 more source
Three Biologic-Naïve Patients with Allergic Bronchopulmonary Aspergillosis Showing Significant Clinical Improvement with Tezepelumab. [PDF]
Yamaguchi M +4 more
europepmc +1 more source
Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang +3 more
wiley +1 more source
Macrophage Immunometabolism in Pulmonary Homeostasis and Chronic Lung Diseases. [PDF]
Xie C +9 more
europepmc +1 more source

