Results 171 to 180 of about 106,829 (304)

Phosphodiesterase signaling in asthma: mechanistic insights and emerging therapeutic strategies. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Alnusayri A, Al-Kuraishy HM, Alexiou A, Papadakis M, Faheem SA, Alruwaili M, Batiha GE.   +6 more
europepmc   +1 more source

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

Allergy, EarlyView.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton, Manuel A. R. Ferreira, Wei Keat Lim, Carlo Sidore, Matthew F. Wipperman, Wenzhen Ge, Xue Song, Changming Xia, Julie E. Horowitz, Andrea T. Hooper, Sara C. Hamon, Jennifer Maloney, Jamie M. Orengo, Zhen Chen, Stephanie Amato Ricci, Bolanle Akinlade, Aris Baras, Gary Herman, Brandy L. Bennett, George D. Yancopoulos   +19 more
wiley   +1 more source

Metabolic licensing at the dendritic cell-NK cells immune synapse in viral asthma exacerbations. [PDF]

Front Immunol
Chen YJ, Bassi GS, Yang YQ.
europepmc   +1 more source

A Comprehensive Review of Natural Products Against Allergic Rhinitis and Asthma: From Sensitization to Chronic Remodeling. [PDF]

Int J Mol Sci
Zhang X, Zhou W, Zhang J, Liu C.
europepmc   +1 more source

Is Asthma Remission a New Achievable Goal? A Review of the Current Drug‐Related Evidence and Predictors

Allergy, EarlyView.
ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin, Giulia Marcassa, Bianca Olivieri, Gianenrico Senna, Marco Caminati   +4 more
wiley   +1 more source

Impact of asthma on mouth breathing, occlusion and salivary parameters in a group of school-aged children: a cross-sectional study. [PDF]

BMC Oral Health
ALQassab ZHJ, Elkaragy ES, Soliman RS, Dowidar KML.   +3 more
europepmc   +1 more source

Rapid Human Skin Barrier Disruption by Sodium Dodecyl Sulfate and Associated Molecular Mechanisms

Allergy, EarlyView.
Short‐term exposure to SDS rapidly disrupts human skin barrier integrity within minutes, as detected by real‐time electrical impedance spectroscopy. SDS‐induced barrier dysfunction is driven by oxidative stress, leading to suppression of immune/barrier mediators and activation of stress, lipid remodeling, and epidermal differentiation pathways ...
Manru Li, Huseyn Babayev, Paolo D'Avino, Can Zeyneloğlu, Ceren Bicer, Duygu Yazici, Yagiz Pat, Per Svedenhag, Nicolas Gaudenzio, Cezmi A. Akdis, Yasutaka Mitamura   +10 more
wiley   +1 more source

Current and Emerging Biologic Therapies for Severe Asthma. [PDF]

Drugs
Cazzola M, Matera MG, Ora J, Calzetta L, Rogliani P.   +4 more
europepmc   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Asthma management in pregnancy and lactation: A review of current evidence and best practice recommendations. [PDF]

NPJ Prim Care Respir Med
Gleeson M, McCarthy C, Shaughnessy FO, Carroll J, Long D, Doyle LM, Ryan DM.   +6 more
europepmc   +1 more source