Results 151 to 160 of about 3,604,842 (297)

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Dihydroartemisinin alleviates allergic airway inflammation by suppressing the PI3K-AKT signaling axis: integrated network pharmacology and experimental validation. [PDF]

Respir Res
Ouyang S, Chen D, Li H, Deng J, Xie Y, Chen S, Lian X, Huang G, Huang X.   +8 more
europepmc   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Mapping structural-immune crosstalk in asthma. [PDF]

Life Med
Chen L, Jin YX, Sun JL.
europepmc   +1 more source

ANTI-ASTHMATIC AGENT ZILEUTON ATTENUATES Ca2+ RESPONSES, INDUCED BY NEUROLEPTIC TRUFLUOPERAZINE, IN MACROPHAGES

Neuroscience for Medicine and Psychology, 2020
Lidiya Milenina, Zoya Krutetskaya, Victor Antonov, Nina Krutetskaya   +3 more
openaire   +1 more source

The Evolution of Sesame Seed Allergy Over Time

Allergy, EarlyView.
This study analyzes the natural history of sesame over time and the changes in biomarkers between sesame allergic and sesame sensitised but tolerant children. The period prevalence of sesame allergy increased from 0.5% between 12 and 36 m to 1.5% between 7 and 12 y children in the EAT‐On study with 10 children developing new sesame allergy. Sesame‐sIgE
Ru‐Xin Foong, George Du Toit, Henry T. Bahnson, Ronald van Ree, Suzana Radulovic, Serge A. Versteeg, Joanna Craven, Matthew Kwok, Zainab Jama, Helen A. Brough, Kirsty Logan, Michael R. Perkin, Carsten Flohr, Alexandra F. Santos, Gideon Lack   +14 more
wiley   +1 more source

Fucoidan attenuates airway remodeling in asthmatic mice. [PDF]

Biomed Rep
Wang X, Qi Y, Hu Y, Zhang S, Hu L, Guan J, Guan R.   +6 more
europepmc   +1 more source

Studies on synthetic approaches to novel anti-asthmatic agents with heterolignan frameworks

Studies on synthetic approaches to novel anti-asthmatic agents with heterolignan frameworks
論文の内容の要旨及び論文審査の結果の要旨
openaire   +1 more source

Navigating Oral Food Challenges in Clinical Trials to Keep the Science Moving Forward

Allergy, EarlyView.
ABSTRACT The oral food challenge (OFC) has long been the reference standard for food allergy diagnosis, as well as to confirm natural development of oral tolerance. The utilization of OFCs has significantly broadened from its role in defining disease to defining participant eligibility, individual allergen reactivity thresholds and treatment outcomes ...
Edwin H. Kim, J. Andrew Bird, Helen A. Brough, David M. Fleischer, Stacie M. Jones, Ildiko Kun, Wayne Shreffler, Claire Van Eenwyk, Brian P. Vickery, Julie Wang, Alexandra F. Santos   +10 more
wiley   +1 more source

Long-term medical support after definitive surgery for esophageal atresia: analysis using a national inpatient database in Japan. [PDF]

Pediatr Surg Int
Yanagida Y, Aso S, Fujiogi M, Kirino K, Ishimaru T, Santo K, Uehara S, Taguchi T, Yoshimura K, Yasunaga H, Fujishiro J.   +10 more
europepmc   +1 more source