Results 201 to 210 of about 32,319 (328)

Allergen-induced asthmatic reactions with marked bronchial eosinophilia in guinea pigs and inhibitory effect of AL-3264, an anti-allergic agent.

, 1994
MARI NOGAMI, Chikako Sakaki, Masayasu Tanaka, Yoshimasa Okazaki, Kunihiko Takeyama   +4 more
openalex   +1 more source

Role of Antimicrobial Peptides in the Pathogenesis of Atopic Dermatitis

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by barrier dysfunction, immune dysregulation, and microbial dysbiosis. Recent studies have highlighted the multifaceted roles of antimicrobial peptides (AMPs) both as innate defenders against microbial invasion and as regulators of immune responses and skin barrier ...
Ge Peng, Alafate Abudouwanli, Quan Sun, Yi Tan, Wanchen Zhao, Mengyao Yang, Shan Wang, Hideoki Ogawa, Ko Okumura, François Niyonsaba   +9 more
wiley   +1 more source

Biologic Therapy in Severe Asthma: A Phenotype-Driven and Targeted Approach. [PDF]

J Clin Med
D'Amato M, Pastore D, Lupia C, Candia C, Bruni A, Garofalo E, Longhini F, Maglio A, Petrone A, Vatrella A, Pelaia G, Pelaia C.   +11 more
europepmc   +1 more source

War and Peace: Ogawa Takemitsu's Theological Engagement with State and Religion

Journal of Religious History, EarlyView.
The Manchurian Incident of 1931 marked a pivotal moment in the rise of Japanese fascism. During the period from this incident until the Pacific War's defeat, dissent from the state's control was not tolerated, leading to coercive measures in religious communities. The Christian community, rather than devising theological reasoning to resist the state's
Eun‐Young Park, Do‐Hyung Kim
wiley   +1 more source

Drugs Used in the Treatment of Viral Infections for the Prevention of Airway Remodeling in Asthma. [PDF]

Mediators Inflamm
Wieczfinska J, Pawliczak R.
europepmc   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Three Biologic-Naïve Patients with Allergic Bronchopulmonary Aspergillosis Showing Significant Clinical Improvement with Tezepelumab. [PDF]

J Asthma Allergy
Yamaguchi M, Yamazaki A, Nakagawa H, Kinose D, Nakano Y.   +4 more
europepmc   +1 more source

Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis

Allergy, EarlyView.
This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino, Juno Kim, Manru Li, Philipp Gessner, Patrick Westermann, Yagız Pat, Carina Beha, Claudia Traidl‐Hoffmann, Jeremy Bost, Nicolas Gaudenzio, Christoph B. Messner, Cezmi A. Akdis, Yasutaka Mitamura   +12 more
wiley   +1 more source

Thioredoxin-interacting protein as a crucial regulator in asthma exacerbation induced by copper oxide nanoparticles in a mouse model. [PDF]

Redox Biol
Kim WI, Pak SW, Park SH, Jin BR, Lee J, Park MJ, Moon C, Yoon WK, Kim SH, Shin IS, Kim JC.   +10 more
europepmc   +1 more source

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

Allergy, EarlyView.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat, Duygu Yazici, Can Zeyneloglu, Huseyn Babayev, Sena Ardicli, Asuncion Garci‐Sanchez, Xiangting Bu, Anja Heider, Oliva Giannelli Viscardi, Lihong Chang, Sheri Simmons, Anthony Almada, Christine Avena, Tye Jensen, Raja Dhir, Ismail Ogulur, Cezmi A. Akdis   +16 more
wiley   +1 more source