Results 251 to 260 of about 106,829 (304)

Nanozymes as Emerging Therapeutics for Asthma: A Redox-Responsive and Immunomodulatory Strategy. [PDF]

open access: yesBiomedicines
El-Morsy MT   +12 more
europepmc   +1 more source

Total alkaloids of <i>Leonurus</i> alleviate allergic asthma and inflammation responses by inhibiting hypoxia-induced factor-1⍺-mediated mast cell activation. [PDF]

open access: yesFront Pharmacol
Zheng Y   +12 more
europepmc   +1 more source

One size does not fit all: uncontrolled T2 inflammation on tezepelumab-a case series. [PDF]

open access: yesAllergy Asthma Clin Immunol
Tardif A   +3 more
europepmc   +1 more source
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Synthesis and biological evaluation of Ginsenoside Compound K analogues as a novel class of anti-asthmatic agents

Bioorganic and Medicinal Chemistry Letters, 2019
Ginsenoside Compound K (CK) showed potent activity against IgE for the treatment of asthma. A series of CK analogues were then synthesized by straightforward procedures. The in vivo anti-IgE activity evaluations using the OVA-induced asthmatic mouse model revealed preliminary SARs of the CK analogues, which showed that the sugar type, modifications on ...
Sumei Ren, Ning Ding, Yingxia Li
exaly   +3 more sources

Discovery of a novel series of α-terpineol derivatives as promising anti-asthmatic agents: Their design, synthesis, and biological evaluation

European Journal of Medicinal Chemistry, 2018
A series of novel α-terpineol derivatives were designed and synthesized through structural derivatization of the tertiary hydroxyl moiety or reduction of the double bond. Of the resulting compounds, eight compounds enhanced relaxation of airway smooth muscle (ASM) compared to the α-terpineol precursor, and four compounds (4a, 4d, 4e, and 4i)were ...
Wanping Zhu, Yuji Wang, Yongzhou Hu
exaly   +3 more sources

Anti-asthmatic agents alleviate pulmonary edema by upregulating AQP1 and AQP5 expression in the lungs of mice with OVA-induced asthma

Respiratory Physiology and Neurobiology, 2012
Ovalbumin (OVA)-induced asthma in mouse lungs causes changes in the mRNA and protein levels of aquaporins (AQPs). AQP expression was examined in the presence of various anti-asthmatic agents, including dexamethasone, ambroxol, and terbutaline. The influence of these agents on OVA-induced airway inflammation was also evaluated.
Chunling Dong, Kui Xiao, Zhongsen Ma
exaly   +3 more sources

Use of anti-asthmatic drugs in Italy: analysis of prescriptions in general practice in the light of guidelines for asthma treatment

open access: yesEuropean Journal of Clinical Pharmacology, 2002
Our aim was to analyse anti-asthmatic drug utilisation in primary health care in a Northern Italian region in the light of guidelines for asthma treatment.
Elisabetta Poluzzi   +2 more
exaly   +2 more sources

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