Results 71 to 80 of about 1,071,340 (389)

Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens. [PDF]

, 2017
The fast development of multi-drug resistant (MDR) organisms increasingly threatens global health and well-being. Plant natural products have been known for centuries as alternative medicines that can possess pharmacological characteristics, including ...
Alsaadi, Abrar I, Husseiny, Mohamed I, Ibrahim, Ashraf S, Khitrov, Gregory, Noreddin, Ayman M, Soliman, Sameh SM, Youssef, Eman G   +6 more
core   +2 more sources

A review on synthetic account of 1,2,4-oxadiazoles as anti-infective agents

Molecular diversity, 2022
Most of the currently marketed drugs consist of heterocyclic scaffolds containing nitrogen and or oxygen as heteroatoms in their structures. Several research groups have synthesized diversely substituted 1,2,4-oxadiazoles as anti-infective agents having ...
Tejas M. Dhameliya, Shrddhaba J. Chudasma, Tanvi M. Patel, B. Dave   +3 more
semanticscholar   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Investigation of antimicrobial activity of silver and copper citrate for the development of pharmaceuticals preparations

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
The fast formation of microbial resistance to antibiotics creates necessity of search for new alternative antimicrobial drugs. Aim. To study the specific antimicrobial activity of silver citrate and copper citrate for the purpose of pharmaceutical ...
Z. N. Polova
doaj   +1 more source

Empiema Necessitatis: reporte de un caso

Medicina U.P.B., 2020
La formación de un absceso que se inicia en el espacio pleural y se extiende hacia los tejidos adyacentes se conoce como Empiema Necessitatis, es una complicación rara, más aún si es secundaria a traumatismo.
Maria Antonia Rendón García, Jaime Andrés Giraldo   +1 more
doaj   +1 more source

The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria [PDF]

, 2008
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
A Baslé, A Baslé, A Bryskier, A Davin-Regli, A Davin-Régli, A Doménech-Sánchez, A Doménech-Sánchez, A Loli, A Mena, A Mena, A Prilipov, A Thiolas, A Thiolas, AA Medeiros, AH Delcour, AM Berezhkovskii, AM Giuliodori, AS Low, C Bornet, C Bornet, C Bosi, C Danelon, C Danelon, C Rodrigues, C Sheridan, Chloë E. James, D Jeanteur, D Szabó, DJ Wolter, E Dé, E Elliott, E Sugawara, EM Nestorovich, EM Nestorovich, F Yoshimura, FM Kaczmarek, G Schwarz, GA Jacoby, GE Schulz, H Nikaido, H Nikaido, H Nikaido, H Samartzidou, H Samartzidou, J Bredin, J Chevalier, J Chevalier, J-M Pagès, JC Cai, Jean-Marie Pagès, JM Bower, K Poole, L Kullman, L Martínez-Martínez, LB Rice, LJ Piddock, LP Randall, M Ceccarelli, M Guillier, M Luckey, M Malléa, M Olesky, M Olesky, M Viveiros, MA Kohanski, Mathias Winterhalter, MM Ochs, N El Amin, P Valentin-Hansen, R Dutzler, R Iyer, R Iyer, R Koebnik, RE Hancock, RN Charrel, S Biswas, S Blot, S Hernández-Allés, S Hernández-Allés, S Nekolla, S Vidal, S Vidal, SF Epp, SM Bezrukov, SM Bezrukov, SR Norrby, SW Cowan, T Ferenci, T Mach, UO Hasdemir, V Simonet, V Simonet, WL Veal, WM Shafer, WR Bauer, XZ Li   +95 more
core   +1 more source

Vitellogenin from the Silkworm, Bombyx mori: An Effective Anti-Bacterial Agent

PLoS ONE, 2013
Silkworm, Bombyx mori, vitellogenin (Vg) was isolated from perivisceral fat body of day 3 of pupa. Both Vg subunits were co-purified as verified by mass spectrometry and immunoblot. Purified Vg responded to specific tests for major posttranslational modifications on native gels indicating its nature as lipo-glyco-phosphoprotein.
Nitin Kumar Singh, Britto Cathrin Pakkianathan, Manish Kumar, Tulika Prasad, Mani Kannan, Simone König, Muthukalingan Krishnan   +6 more
openaire   +4 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Dynamics of Antibiotic Prescription in Royal Hampshire County Hospital in November 2016: A Prospective Study

International Journal of Medical Students, 2017
Background: Antimicrobial Stewardship and The Start Smart – Then Focus strategy provide guidelines aimed at improving the increasing trend of antibiotic resistance.
Kathrine Lee-A-Ping, Kordo Saeed, Matthew Dryden, Gavin Sim   +3 more
doaj   +1 more source

Ocular Antibiotic Utilisation across Aotearoa/New Zealand

Antibiotics, 2023
Ocular antibiotics are integral to the prevention and treatment of bacterial ocular infections. This study aimed to describe their utilisation across New Zealand according to patient and healthcare factors.
Isabella M. Y. Cheung, Simon Horsburgh, Mohammed Ziaei, Akilesh Gokul   +3 more
doaj   +1 more source