Results 61 to 70 of about 639,638 (307)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Non-leaching antimicrobial surfaces through polydopamine bio-inspired coating of quaternary ammonium salts or an ultrashort antimicrobial lipopeptide. [PDF]

, 2012
Bacterial fouling on surfaces significantly increases the resistance of bacteria toward antibiotics, which leads to medical complications and a corresponding financial burden.
Bauer, Michael, Gopin, Anna, Rahimipour, Shai, Shalev, Tel, Stark, Robert W.   +4 more
core   +1 more source

Vitellogenin from the Silkworm, Bombyx mori: An Effective Anti-Bacterial Agent

PLoS ONE, 2013
Silkworm, Bombyx mori, vitellogenin (Vg) was isolated from perivisceral fat body of day 3 of pupa. Both Vg subunits were co-purified as verified by mass spectrometry and immunoblot. Purified Vg responded to specific tests for major posttranslational modifications on native gels indicating its nature as lipo-glyco-phosphoprotein.
Nitin Kumar Singh, Britto Cathrin Pakkianathan, Manish Kumar, Tulika Prasad, Mani Kannan, Simone König, Muthukalingan Krishnan   +6 more
openaire   +4 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Physicochemical Characteristics of Nanoliposome Garlic (Allium sativum L.) Essential Oil and Its Antibacterial Effect on Escherichia coli O157:H7 [PDF]

Journal of Food Quality and Hazards Control, 2017
Background: Escherichia coli O157:H7 is a Gram-negative and facultative anaerobic food-borne bacterial pathogen. The major purpose of this study was to evaluate physicochemical characteristics of nanoliposome garlic Essential Oil (EO) and its ...
A. Zabihi, A. Akhondzadeh Basti, G. Amoabediny, A. Khanjari, J. Tavakkoly Bazzaz, F. Mohammadkhan, A. Hajjar Bargh, E. Vanaki   +7 more
doaj  

Ocular Antibiotic Utilisation across Aotearoa/New Zealand

Antibiotics, 2023
Ocular antibiotics are integral to the prevention and treatment of bacterial ocular infections. This study aimed to describe their utilisation across New Zealand according to patient and healthcare factors.
Isabella M. Y. Cheung, Simon Horsburgh, Mohammed Ziaei, Akilesh Gokul   +3 more
doaj   +1 more source

Serological Survey of Antibodies to Mannheimia haemolytica and Pasteurella multocida in Camelids from Argentina [PDF]

, 2017
South American camelids are a source of livestock wealth in Andean countries. In Argentina,there is little information about camelid pathogens, and most of the literature data available areseroprevalence works against virus.
Calcagno, M. L., Canellada, Andrea Mercedes, Castro, Marisa Silvia, Díaz, Ailén Magalí, Ledesma, Martin Manuel, Leoni, Juliana, Manghi, Marcela Alejandra   +6 more
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Investigation of antimicrobial activity of silver and copper citrate for the development of pharmaceuticals preparations

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
The fast formation of microbial resistance to antibiotics creates necessity of search for new alternative antimicrobial drugs. Aim. To study the specific antimicrobial activity of silver citrate and copper citrate for the purpose of pharmaceutical ...
Z. N. Polova
doaj   +1 more source

A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages [PDF]

, 2017
Macrophages produce genotoxic agents, such as reactive oxygen and nitrogen species, that kill invading pathogens. Here we show that these agents activate the DNA damage response (DDR) kinases ATM and DNA-PKcs through the generation of double stranded ...
Akira, Akira, Alaoui-El-Azher, Amiri, Anand, Bakkenist, Bednarski, Bednarski, Blunt, Bredemeyer, Bredemeyer, Callen, Callén, Chatzinikolaou, Chumduri, Ciccia, Clausen, Cuevas-Ramos, Edelson, Erttmann, Fedor, Floyd, Frank, Frisan, Griffith, Guerra, Guo, Helmink, Helmink, Herrtwich, Hsieh, Huang, Innes, Jackson, Jinadasa, Karo, Kraal, Kuziel, Lamkanfi, Laubach, Lilley, MacMicking, McNab, Mosser, Nathan, Nesić, Nirodi, Nougayrède, Nunes, Okamura, Pollock, Radi, Ritchie, Rogakou, Roth, Rouleau, Schoenborn, Schwab, Sekiguchi, Sherman, Shi, Tamir, Theunissen, von Moltke, Weitzman, Witte, Wu, Zha   +67 more
core   +3 more sources