Results 61 to 70 of about 2,669 (210)

Outpatient parenteral antimicrobial therapy (OPAT) programs for pediatric patients: A systematic review

International Journal of Infectious Diseases
Objective: The aim of this study is to guide other investigators in designing and implementing an appropriate pediatric outpatient parenteral antimicrobial therapy (OPAT) program in healthcare settings.
Pablo Ciudad-Gutiérrez, Paloma Suárez-Casillas, Laura Herrera-Hidalgo, Marta Mejías-Trueba, María José Muñoz-Vilches, Olaf Neth, Marta Moleón-Ruiz, Flora López-González, María Victoria Gil-Navarro, Ana Belén Guisado-Gil   +9 more
doaj   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Multifunctional Thiolated Hyaluronic Acid‐graft‐PEDOT Dressing With Antifouling, On‐Demand Drug Delivery and Electrical Stimulation for Wound Healing

Advanced Healthcare Materials, EarlyView.
A multifunctional P(EDOT‐co‐EDOT‐g‐THA) dressing acts as a dynamic biointerface integrating antifouling capability, on‐demand drug delivery, and electrical stimulation. It achieves electrochemically triggered thiolated hyaluronic acid (THA) release while modulating cellular responses for wound healing application.
Jingwen Yang, Jiwon Hong, Anthony Phillips, Bicheng Zhu, Jenny Malmstrom, Devon T. Bryant, Alireza Akbarinejad, Lisa I. Pilkington, Jadranka Travas‐Sejdic   +8 more
wiley   +1 more source

Rare‐Earth–Functionalized Carbon Dot Hydrogels as Mechanically Robust Antibacterial Wound Dressings

Advanced Healthcare Materials, EarlyView.
The schematic depicts a dynamically cross‐linked PVA hydrogel network in which reversible borate ester bonds and hydrogen‐bonding interactions integrate lanthanum‐doped carbon dots (La‐CDs) and dipotassium glycyrrhizinate (DPG) to form a mechanically robust, multifunctional matrix.
Shih‐Han Tsai, Ramadhass Keerthika Devi, Muthusankar Ganesan, Guo‐Ping Chang Chien, Chun Che Lin   +4 more
wiley   +1 more source

Methylene blue-containing liposomes as new photodynamic anti-bacterial agents

Journal of Materials Chemistry B, 2017
Novel cationic liposomes containing the photo-activatable drug methylene blue (MB) strongly enhance the antibacterial activity of MB towards Gram-negative bacteria and improve biofilm penetration.
BOCCALINI, GIULIA, CONTI, LUCA, MONTIS, COSTANZA, BANI, DANIELE, BENCINI, ANDREA, BERTI, DEBORA, GIORGI, CLAUDIA, MENGONI, ALESSIO, VALTANCOLI, BARBARA   +8 more
openaire   +2 more sources

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Vitellogenin from the Silkworm, Bombyx mori: An Effective Anti-Bacterial Agent

PLoS ONE, 2013
Silkworm, Bombyx mori, vitellogenin (Vg) was isolated from perivisceral fat body of day 3 of pupa. Both Vg subunits were co-purified as verified by mass spectrometry and immunoblot. Purified Vg responded to specific tests for major posttranslational modifications on native gels indicating its nature as lipo-glyco-phosphoprotein.
Nitin Kumar Singh, Britto Cathrin Pakkianathan, Manish Kumar, Tulika Prasad, Mani Kannan, Simone König, Muthukalingan Krishnan   +6 more
openaire   +4 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Adverse drug reaction monitoring of commonly prescribed antimicrobial agents in patients at Rama medical college, hospital and research centre, Kanpur

Asian Journal of Medical Sciences
Background: An adverse drug reaction (ADR) is defined as a harmful or unpleasant reaction due to the use of a drug and may cause different types of effects, such as side effects.
Princ Bgheal , Piyush Verma , Bhopal Chandra Vurimi , Nilam Nigam , Kriti Jalota , Syed Shadman Ahmad , Priyanka Pal , Anjani Devi Nelavala   +7 more
doaj   +1 more source