Results 41 to 50 of about 392,756 (261)

Antimicrobial properties of nanomolecules: potential candidates as antibiotics in the era of multi-drug resistance [PDF]

open access: yesEpidemiology and Health, 2015
OBJECTIVES: The emergence of multi-drug resistance among various microbial pathogens has been a cause of serious concern to the medical world, limiting the choice of antibiotics.
Venkataramana Kandi, Sabitha Kandi
doaj   +1 more source

Farmacocinética y farmacodinámica, implicación en un uso más racional de los antimicrobianos en pediatría Pharmacokinetics and pharmacodynamics, implications in the more rational usage of antimicrobials in pediatrics

open access: yesRevista Médica Electrónica, 2009
La farmacodinámica describe la compleja interrelación que se establece entre el perfil farmacocinético del antimicrobiano y la susceptibilidad in vitro de la bacteria.
Amaury Noda Albelo, Arturo Vidal Tallet
doaj  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Antibacterial and Antioxidant Properties of Methanolic Extracts of Some Native Edible Plants Collected from Kermanshah, Western Iran

open access: yesJournal of Food Quality and Hazards Control, 2017
Background: There is growing demand to improve physicochemical, microbiological, and sensory properties of fresh foods using natural herbal antimicrobial and antioxidant compounds.
Y. Shahbazi
doaj  

Pneumococcal Osteomyelitis: Report of One Case

open access: yesPediatrics and Neonatology, 2008
Acute osteomyelitis is uncommon in pediatric patients, affecting one in five thousand children younger than the age of thirteen. Bone infection caused by Streptococcus pneumoniae is extremely rare, accounting for only 1.3% of acute osteomyelitis in ...
W. Luke Huang   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Comparison of Antimicrobial Activity of Chitosan Nanoparticles Loaded with Amoxicillin with Free Amoxicillin against Some Gram Positive and Gram Negative Bacteria

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2018
Background and Objectives: Antibiotic resistance has prepared the way for substituting new therapeutic methods. Studies have indicated that nanoformulated antimicrobial agents have better therapeutic effects.
Asma Toraji   +2 more
doaj  

Subacute hematogenous osteomyelitis of the fibula

open access: yesThe Pan African Medical Journal, 2020
A ten years old patient consulted us for lower right limb pain and fever (38.2°C). There were inflammatory signs and palpation pain in relation to the right fibula. Biology was disturbed with white blood cells at 17.470 el/mm³, a sedimentation rate at 50
Zied Jlalia, Dhia Kaffel
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

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