Results 41 to 50 of about 639,638 (307)

Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]

, 2013
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown, Caron, Cars, Cars, Collignon, Dagan, DiNubile, Drlica, Essack, Fox, Geli, Goren, Gould, Guillemot, Harris, Hurdle, Huttner, Isha, Madurell, Masterton, Michalsen, Mitchison, Mitchison, Molstad, Sharma, Solapure, Talbot, Thomas   +27 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Evaluation of in Vitro Antimicrobial Effects of Aqueous Extract of Tribulus terrestris Against Oral Bacteria

Medical Laboratory Journal, 2021
Background and objectives: Medicinal plants have long been considered as one of the most important pillars of traditional medicine. Existing challenges in the treatment of diseases, particularly infectious diseases, are major drivers for herbal medicine ...
Zahra Kiani, Pouria Mohammad Parast Tabas, khashayar khalilpour, Mahjoube Goldani Moghadam, Majid Zare_Bidaki   +4 more
doaj  

WHAT IS THE EPIDEMIOLOGICAL PROFILE OF ACUTE HAND INFECTIONS AT A HOSPITAL IN SAO PAULO? [PDF]

Acta Ortopédica Brasileira
Objective: To determine the epidemiological profile of patients treated at a philanthropic hospital specialized in Orthopedics and Traumatology, located in a significant urban center, and evaluate the efficacy of initial empirical antibiotic treatment ...
Thomas Yi Teh Lee, Lucas Alves Nemer, Alessandro Ayres Vianna, Yussef Ali Abdouni, Fabrício Luz Cardoso, Antonio Carlos da Costa   +5 more
doaj   +1 more source

Antimicrobial properties of nanomolecules: potential candidates as antibiotics in the era of multi-drug resistance [PDF]

Epidemiology and Health, 2015
OBJECTIVES: The emergence of multi-drug resistance among various microbial pathogens has been a cause of serious concern to the medical world, limiting the choice of antibiotics.
Venkataramana Kandi, Sabitha Kandi
doaj   +1 more source

Prescribing practices of primary-care veterinary practitioners in dogs diagnosed with bacterial pyoderma [PDF]

, 2014
Concern has been raised regarding the potential contributions of veterinary antimicrobial use to increasing levels of resistance in bacteria critically important to human health.
A Hillier, A Mateus, A Wayne, AD Radford, AD Watson, Anke Hendricks, B Kirkwood, C Noli, CP Murphy, David C Brodbelt, DL Wells, DW Scott, DW Scott, EJ Pleydell, EM Lund, FC Tenover, IS Mason, J Bannoehr, J Cd, Jennifer F Summers, JF Summers, JR Fitzgerald, JS Weese, K Gortel, K Odensvik, L Beco, L Beco, LA Hughes, LM Freeman, LS Barter, M Escher, M Rantala, N Murayama, National Organisation of Animal Health (Great Britain) (NOAH), OM Briggs, PB Hill, PB Hill, PJ Ihrke, RK Anderson, T Sasaki, VJ Adams, WM Sischo   +41 more
core   +2 more sources

Scorpine, an anti‐malaria and anti‐bacterial agent purified from scorpion venom [PDF]

FEBS Letters, 2000
A novel peptide, scorpine, was isolated from the venom of the scorpion Pandinus imperator, with anti‐bacterial activity and a potent inhibitory effect on the ookinete (ED50 0.7 μM) and gamete (ED50 10 μM) stages of Plasmodium berghei development. It has 75 amino acids, three disulfide bridges with a molecular mass of 8350 Da.
Conde, Renaud, Zamudio, Fernando Z., Rodrı́guez, Mario H., Possani, Lourival D.   +3 more
openaire   +2 more sources

Efficacy of Zinc Pyrithione as A Novel Anti-Bacterial Coating Agent

Recent Progress in Materials, 2023
Zinc pyrithione (ZPT) is used to prevent microbial degradation and deterioration of manufacturing starting materials such as plastics, polymers, and latexes. The main objective of this study was to evaluate the anti-bacterial properties of ZPT. Currently, there is insufficient data on the effect of ZPT on viability of commonly encountered bacterial ...
Sumita Jain, Noufa Khan, Yena Park, Densen Cao, Daniel CN Chan   +4 more
openaire   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Inflammatory cytokines and biofilm production sustain Staphylococcus aureus outgrowth and persistence: A pivotal interplay in the pathogenesis of Atopic Dermatitis [PDF]

, 2018
Individuals with Atopic dermatitis (AD) are highly susceptible to Staphylococcus aureus colonization. However, the mechanisms driving this process as well as the impact of S. aureus in AD pathogenesis are still incompletely understood.
A Matlow, A Oliveira de, A Sandilands, A Sonesson, AC Krakowski, AD Irvine, AM Bowcock, B Cabanillas, B Han, BC Friedman, C Fux, C Pascolini, CI Ewing, CL Jinnestal, D Ellinghaus, D Lebeaux, DY Koller, DYM Leung, DYM Leung, E Clark, E Weinberg, EC Clark, EG Domenico Di, EG Domenico Di, FJ Bath-Hextall, FR Menegotto, G Stinco, GF Gad, GL Hazelbauer, GM O’Regan, GM O’Regan, GU Meduri, H Akiyama, HB Allen, HH Kong, I Marenholz, I Nomura, J Oh, J Schmitt, JH Lee, JM Hanifin, JQ Gong, K Becker, K Breuer, K Krause, KL Hon, L Chronopoulou, L Paternoster, LA O’Neill, LP Girard, M Bhattacharya, M Denis, M Mehrotra, M Niebuhr, MD Howell, ML Schuttelaar, MS Haque, P Castaneda, P Chavant, PH Hoeger, R Lever, R Saginur, RA McLaughlin, RL Gallo, RM Klevens, RP Howlin, S Eriksson, S Kanangat, S Kezic, S Kezic, S Stutte, S Weidinger, SE Hill, SE Satorres, SE Satorres, SH Cho, SH Hung, SJ Gilani, SX Xu, T Bieber, T Biedermann, T Kobayashi, T Nakatsuji, T Werfel, TX Nhan, UG Meduri, V Dossow von, W Abramovits, Z Ikezawa   +88 more
core   +1 more source