Results 31 to 40 of about 375,460 (285)

WHAT IS THE EPIDEMIOLOGICAL PROFILE OF ACUTE HAND INFECTIONS AT A HOSPITAL IN SAO PAULO? [PDF]

Acta Ortopédica Brasileira
Objective: To determine the epidemiological profile of patients treated at a philanthropic hospital specialized in Orthopedics and Traumatology, located in a significant urban center, and evaluate the efficacy of initial empirical antibiotic treatment ...
Thomas Yi Teh Lee, Lucas Alves Nemer, Alessandro Ayres Vianna, Yussef Ali Abdouni, Fabrício Luz Cardoso, Antonio Carlos da Costa   +5 more
doaj   +1 more source

Phlegmonous gastritis: Evolving from surgical to medical disease

IDCases, 2023
We present a case of phlegmonous gastritis, which is a rare, life-threatening infection involving transmural inflammation of the stomach of multiple possible etiologies.
Michael T. Czapka, Stephen J. Schrantz
doaj   +1 more source

Efficacy of Zinc Pyrithione as A Novel Anti-Bacterial Coating Agent

Recent Progress in Materials, 2023
Zinc pyrithione (ZPT) is used to prevent microbial degradation and deterioration of manufacturing starting materials such as plastics, polymers, and latexes. The main objective of this study was to evaluate the anti-bacterial properties of ZPT. Currently, there is insufficient data on the effect of ZPT on viability of commonly encountered bacterial ...
Sumita Jain, Noufa Khan, Yena Park, Densen Cao, Daniel CN Chan   +4 more
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Evaluation of different detection methods of biofilm formation in the clinical isolates

Brazilian Journal of Infectious Diseases
BACKGROUND: Microorganisms growing in a biofilm are associated with chronic and recurrent human infections and are highly resistant to antimicrobial agents.
Afreenish Hassan, Javaid Usman, Fatima Kaleem, Maria Omair, Ali Khalid, Muhammad Iqbal   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Initial respiratory specimen bacteriology and isolates susceptibility to antimicrobials in promptly intubated chronic obstructive pulmonary disease adults - single-center two-year experience [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2019
Introduction/Objective. Chronic obstructive pulmonary disease (COPD) exacerbation is mostly triggered by infectious agents and seriously compromises the patient’s quality of life and predicts a poor outcome of the disease as well.
Gluvić Zoran, Mitrović Bojan, Radojević Biljana, Krasnjuk Andrej, Panić Miloš, Miličević Predrag, Vukčević Miodrag, Tomašević Ratko, Putniković Biljana, Nešković Aleksandar N.   +9 more
doaj   +1 more source

Methylene blue-containing liposomes as new photodynamic anti-bacterial agents

Journal of Materials Chemistry B, 2017
Novel cationic liposomes containing the photo-activatable drug methylene blue (MB) strongly enhance the antibacterial activity of MB towards Gram-negative bacteria and improve biofilm penetration.
BOCCALINI, GIULIA, CONTI, LUCA, MONTIS, COSTANZA, BANI, DANIELE, BENCINI, ANDREA, BERTI, DEBORA, GIORGI, CLAUDIA, MENGONI, ALESSIO, VALTANCOLI, BARBARA   +8 more
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source