Results 71 to 80 of about 639,638 (307)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Dynamics of Antibiotic Prescription in Royal Hampshire County Hospital in November 2016: A Prospective Study

open access: yesInternational Journal of Medical Students, 2017
Background: Antimicrobial Stewardship and The Start Smart – Then Focus strategy provide guidelines aimed at improving the increasing trend of antibiotic resistance.
Kathrine Lee-A-Ping   +3 more
doaj   +1 more source

Farmacocinética y farmacodinámica, implicación en un uso más racional de los antimicrobianos en pediatría Pharmacokinetics and pharmacodynamics, implications in the more rational usage of antimicrobials in pediatrics

open access: yesRevista Médica Electrónica, 2009
La farmacodinámica describe la compleja interrelación que se establece entre el perfil farmacocinético del antimicrobiano y la susceptibilidad in vitro de la bacteria.
Amaury Noda Albelo, Arturo Vidal Tallet
doaj  

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

open access: yes, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

Rhamnose Binding Protein as an Anti-Bacterial Agent—Targeting Biofilm of Pseudomonas aeruginosa [PDF]

open access: yesMarine Drugs, 2019
More than 80% of infectious bacteria form biofilm, which is a bacterial cell community surrounded by secreted polysaccharides, proteins and glycolipids. Such bacterial superstructure increases resistance to antimicrobials and host defenses. Thus, to control these biofilm-forming pathogenic bacteria requires antimicrobial agents with novel mechanisms or
Tse-Kai Fu   +10 more
openaire   +3 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

Antibacterial and Antioxidant Properties of Methanolic Extracts of Some Native Edible Plants Collected from Kermanshah, Western Iran

open access: yesJournal of Food Quality and Hazards Control, 2017
Background: There is growing demand to improve physicochemical, microbiological, and sensory properties of fresh foods using natural herbal antimicrobial and antioxidant compounds.
Y. Shahbazi
doaj  

Effectiveness of Durian Peel Extract as A Natural Anti-Bacterial Agent

open access: yesJurnal Rekayasa Kimia & Lingkungan, 2019
Durian (durio zibertinus) is a native tropical fruit from Southeast Asia, especially Indonesia. Durian peel is the highest composition of durian fruit (60-75%), and is still considered as waste that causes environmental problems. This study aimed to analyze the content of secondary metabolites extract, to analyze the anti-bacterial activity of durian ...
Nina Arlofa   +3 more
openaire   +3 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy