Results 91 to 100 of about 2,154,155 (297)

The exopolysaccharide gene cluster Bcam1330-Bcam1341 is involved in Burkholderia cenocepacia biofilm formation, and its expression is regulated by c-di-GMP and Bcam1349 [PDF]

, 2013
In Burkholderia cenocepacia, the second messenger cyclic diguanosine monophosphate (c-di-GMP) has previously been shown to positively regulate biofilm formation and the expression of cellulose and type-I fimbriae genes through binding to the ...
Ryan, Robert P, Givskov, Michael, Fazli, Mustafa, Tolker-Nielsen, Tim, McCarthy, Yvonne   +4 more
core   +1 more source

Limits to growth and what keeps a biofilm finite

, 1999
Two of the factors, shear erosion and diffusive mass transfer, which limit the growth of heterogeneous biofilms are considered. For permeable beds of particulates, with a regulated throughflow, equating shear induced erosion and biofilm growth, leads to ...
Dodds, Ian, Boyle, John D., Stoodley, Paul, Lappin-Scott, Hilary   +3 more
core   +1 more source

Anti-biofilm activity of anti-matrix molecules

Zdorovʹe Rebenka, 2020
The extracellular matrix of biofilms ensures the fixation of the biofilm on the biological surface and the protection of its bacteria from external adverse factors.
А.Е. Abaturov
doaj   +1 more source

Mesoporous Catalytic‐Adsorptive Nanoregulator Orchestrates Biofilm eDNA/LPS Disassembly and TLR9/TLR4 Immune Reprogramming to Resolve Diabetic Foot Infections

Advanced Science, EarlyView.
Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song, Yang Song, Xirui Huang, Xingjin Li, Lifei Gao, Yixiang Wang, Tianbao Zhu, Xiaomin Li, Shuai Wang, Tiancong Zhao, Dongyuan Zhao   +10 more
wiley   +1 more source

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source

Anti-biofilm and anti-inflammatory active diterpene isolated from the fruit of Xylopia benthamii R.E.Fr.

, 2023
Xylopia benthamii (Annonaceae) is a plant with limited phytochemical and pharmacological evidence. Thus, using LC-MS/MS, we performed exploratory analyses of the fruit extract of X.
Patrícia Souza e Silva (13836022), Felipe M. A. da Silva (7205339), Hector H. F. Koolen (7205342), Ana Paula A. Boleti (6106031), Emmanoel V. Costa (2829110), Ludovico Migliolo (128782), Emilly J. S. P. de Lima (15425806), Weider H. P. Paz (10381373), Josean F. Tavares (8769200), Lincoln T. H. Mukoyama (15425812), Nállarett M. Dávila Cardozo (15425809)   +10 more
core   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

Advanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li, Yonglong Li, Jiren Yan, Changming Wang, Jinlong Yu, Feng Jiang, Boyong Wang, Yi Yang, Deyi Ding, Jin Tang, Pei Han, Botao Song, Geyong Guo, Hao Shen   +13 more
wiley   +1 more source

Role of mutation in pseudomonas aeruginosa biofilm development.

, 2009
The survival of bacteria in nature is greatly enhanced by their ability to grow within surface-associated communities called biofilms. Commonly, biofilms generate proliferations of bacterial cells, called microcolonies, which are highly recalcitrant, 3 ...
Collins, Samuel L., Webb, Jeremy S., Conibear Tim C. R., Collins Samuel L., Conibear, Tim C. R., Jeremy S. Webb, Webb Jeremy S., Samuel L. Collins, Samuel L Collins, Tim C R Conibear, Jeremy S Webb, Tim C. R. Conibear   +11 more
core   +1 more source

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

Advanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng, Rui Wang, Dianqi Zhang, Wei Zhang, Jaebum Choo, Fabiao Yu, Shaowen Cheng   +6 more
wiley   +1 more source

Determination of stability and kinetic characterization of lysozyme (isolated from Bacillus subtilis BSN314)

The Microbe
This study investigated the stability and anti-biofilm activity of a lysozyme purified from Bacillus subtilis BSN314. The hypothesis that the enzyme's anti-biofilm effect is concentration- and time-dependent was tested. Lysozyme stability was assessed by
Muhammad Naveed, Sai Wen, Anas Sajjad, Binbin Si, Malik Wajid Hussain Chan, Fenghuan Wang   +5 more
doaj   +1 more source