Results 51 to 60 of about 3,948,358 (329)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

“To Work Black Magic”: Richard Bruce Nugent’s Queer Transnational Insurgency

open access: yesJAm It!, 2019
Within the Harlem Renaissance’s politically charged climate, a discourse of anti-decadence emerged to police the boundaries of racial solidarity and to ward off the public specter of flamboyant homosexuality associated with European aestheticism. However,
Ryan Tracy
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Because We Know

open access: yesJournal of Effective Teaching in Higher Education, 2021
Black mattering is contested terrain. As we write this, more than 25 states and municipalities have proposed or passed legislation banning critical race theory (CRT) and the incorporation of material(s) that upset the normative curricular and pedagogical
Wilson Kwamogi Okello, Terah J. Stewart
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Review of "Possessing Polynesians: The Science of Settler Colonial Whiteness in Hawai`i and Oceania" by Maile Arvin (Duke University Press)

open access: yesLateral, 2020
Arvin explains how dispossessing Polynesians was predicated on a logic of settler colonialism inflected by white supremacy. Casting Polynesians as white—specifically, as “almost white”—as opposed to distancing Polynesians from Caucasians, simultaneously ...
Christine Rosenfeld
doaj   +1 more source

Dark Looks: Sensory Contours of Racism in India [PDF]

open access: yes, 2020
This chapter explores the intersections of caste, color, and class that become visible on the bodies of brown and black women moving through public spaces in India. The authors argue that a pervasive “haptic gaze,” that deploys staring as a prosthetic of
Prasad, Pavithra, Raghavan, Anjana
core  

Queer international relations [PDF]

open access: yes, 2017
Queer International Relations (IR) is not a new field. For more than 20 years, Queer IR scholarship has focused on how normativities and/or non-normativities associated with categories of sex, gender, and sexuality sustain and contest international ...
Richter-Montpetit, Melanie   +1 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

From the Hood to the White House: The Cultural Imaginary of Presidential Blackness in Head of State

open access: yesAmerican Studies in Scandinavia, 2020
This article analyzes the film Head of State’s cultural imaginary of presidential blackness that signifies national progress while sublimating social conflict.
Atalie Gerhard
doaj   +1 more source

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