Results 61 to 70 of about 1,445,530 (305)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Recognizing Anti-blackness in Media and Other Institutions
, 2020 Myra Washington, Associate Professor in Communication and Journalism at The University of New Mexico, discusses how dehumanizing portrayals of Black people in the media desensitizes people to brutal violence against Black people.
Lucero, Marissa
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Towards Black Accompaniment: Deconstructing “Subtle” Anti-Blackness in a Chicanx/Latinx Podcast [PDF]
, 2020 With the rise in visibility of AfroLatinidad and the global reach of the Black Lives Matter movement, non-Black Latinxs have increasingly considered anti-Blackness as an inter- and intra-community issue.
Exford, Jazmine Exford
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Traces of anti-blackness in Cape Verde [PDF]
, 2022 A reflexão proposta toma o caso de Cabo Verde para ilustrar a hipótese de que nem mesmo nas nações africanas pós-coloniais se desmantelou o racismo colonialista do quotidiano e, sobretudo, não se conseguiu demolir a antinegritude como afeto predominante ...
Rocha, Eufémia Vicente +1 more
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Critical Social Work, 2023 Three Black faculty members (i.e., two tenure track Black women faculty and one tenured Black male faculty) recapitulate their experiences through the conceptual frames of four fundamental critical race theory (CRT) tenets: the permanence of racism ...
Raymond Adams +2 more
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
An Introduction to Anti-Black Sanism
, 2023 <p>Sanism is an oppression. It makes normal the practice of discrimination, rejection, silencing, exclusion, low expectations, incarceration, and other forms of violence against people who are othered through mental ‘illness’ diagnosis, history, or even suspicion.
Meerai, Sonia +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Anti-Blackness and Human Monstrosity in Black American Horror Fiction
Introduction: Barely humans, Black horror, and American anti-Blackness -- The monsters of White rage -- The monsters of respectability -- The monsters of not-ness -- The monsters of serial killing -- Conclusion: Eliminating anti-Blackness and its ...
Jenkins, Rafiki, 1967-
core +1 more source