Results 51 to 60 of about 1,445,530 (305)

NAMING RACISM, CONFRONTING ANTI-BLACKNESS: TRANSNATIONAL MEXICAN AMERICAN RACIALIZATION AND COALITION BUILDING [PDF]

open access: yes, 2022
This dissertation seeks to trace a geneology of anti-Blackness within Mexican American and racial identity formation. By understanding the nuanced differences between white supremacy, racism against Mexicans and the structural racism of anti-Blackness, I
Rubalcava, Bianca Sofia
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Anti-Blackness

open access: yesOpen Encyclopedia of Anthropology
‘Anti-Blackness’ refers to a pervasive and deeply entrenched form of dehumanisation and exclusion targeting people racialised as ‘Black’, particularly those of African, Afro-diasporic, and Australasian descent. While often categorised under the broader umbrella of ‘racism’, some scholars argue that anti-Blackness constitutes a distinct formation rooted
openaire   +2 more sources

Review of "Possessing Polynesians: The Science of Settler Colonial Whiteness in Hawai`i and Oceania" by Maile Arvin (Duke University Press)

open access: yesLateral, 2020
Arvin explains how dispossessing Polynesians was predicated on a logic of settler colonialism inflected by white supremacy. Casting Polynesians as white—specifically, as “almost white”—as opposed to distancing Polynesians from Caucasians, simultaneously ...
Christine Rosenfeld
doaj   +1 more source

From the Hood to the White House: The Cultural Imaginary of Presidential Blackness in Head of State

open access: yesAmerican Studies in Scandinavia, 2020
This article analyzes the film Head of State’s cultural imaginary of presidential blackness that signifies national progress while sublimating social conflict.
Atalie Gerhard
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

To Blanch an Ethiop: Motifs of Blackness in The Tempest and Ben Jonson’s Masque of Blackness

open access: yesHumanities
In the period between 2021 and 2022 immediately following the COVID-19 lockdowns, there were 37 professional or academic productions of The Tempest in the United States.
Christina Lynn Gutierrez-Dennehy
doaj   +1 more source

Review of "Skin Theory: Visual Culture and the Postwar Prison Laboratory" by Cristina Visperas (New York University Press)

open access: yesLateral, 2023
In "Skin Theory," Cristina Visperas identifies how the captive body in the postwar era is positioned as the ideal test subject. She does so through a thorough interrogation of Albert Kligman’s primarily dermatological human experiments at Holmesburg ...
Patrick Teed
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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