Results 61 to 70 of about 3,948,358 (329)

Review of "Skin Theory: Visual Culture and the Postwar Prison Laboratory" by Cristina Visperas (New York University Press)

open access: yesLateral, 2023
In "Skin Theory," Cristina Visperas identifies how the captive body in the postwar era is positioned as the ideal test subject. She does so through a thorough interrogation of Albert Kligman’s primarily dermatological human experiments at Holmesburg ...
Patrick Teed
doaj   +1 more source

The Color of Childhood: The Role of the Child/Human Binary in the Production of Anti-Black Racism [PDF]

open access: yes, 2018
The binary between the figure of the child and the fully human being is invoked with regularity in analyses of race, yet its centrality to the conception of race has never been fully explored.
Bernstein R.   +40 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

The Myths of Haji Firuz: The Racist Contours of the Iranian Minstrel

open access: yesLateral, 2021
Every year, around the arrival of the Spring equinox, Iranians in Iran and in diaspora will recognize a minstrel named Haji Firuz with his Nowruz jingle. The inclusion of Haji Firuz during Nowruz festivities has been questioned and challenged for decades;
Beeta Baghoolizadeh
doaj   +1 more source

Dreams/Myths/Histories: Envisioning More Livable World [PDF]

open access: yes, 2019
In “Dreams/Myths/Histories: Envisioning More Livable World” we arrive at the duo-keynote conver- sation between the 2017 keynote speakers: C. Riley Snorton and CeCe McDonald.
McDonald, CeCe, Snorton, C. Riley
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

To Blanch an Ethiop: Motifs of Blackness in The Tempest and Ben Jonson’s Masque of Blackness

open access: yesHumanities
In the period between 2021 and 2022 immediately following the COVID-19 lockdowns, there were 37 professional or academic productions of The Tempest in the United States.
Christina Lynn Gutierrez-Dennehy
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Disentangling engineering education research'santi‐Blackness [PDF]

open access: yesJournal of Engineering Education, 2020
http://deepblue.lib.umich.edu/bitstream/2027.42/191175/2/Holly Jr (2020)_Disentangling engineering education researchs anti-Blackness.pdf ; Published version ; Description of Holly Jr (2020)_Disentangling engineering education researchs anti-Blackness.pdf : Published ...
openaire   +2 more sources

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