Results 31 to 40 of about 16,858 (143)

Anti‐CCP Antibody, a Marker for the Early Detection of Rheumatoid Arthritis

Annals of the New York Academy of Sciences, 2008
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic inflammation of synovial joints. In most cases this will lead to the formation of pannus tissue, ultimately leading to joint destruction. Early diagnosis, coupled with aggressive use of disease‐modifying antirheumatic drugs, has been shown to have a favorable effect on ...
Venrooij, W.J.W. van, Beers, J.J.B.C. van, Pruijn, G.J.M.   +2 more
openaire   +4 more sources

Factors related to seroconversion of anti-cyclic citrullinated peptide antibody after the onset of rheumatoid arthritis: a case-control study and systematic review

Immunological Medicine
Anti-cyclic citrullinated peptide (CCP) antibodies typically present before rheumatoid arthritis (RA) but appear (seroconvert) after disease onset in some patients. This study analyzed factors related to anti-CCP seroconversion.
Yui Kosumi, Ryoko Asano, Aki Sugano, Masaru Yoshimura, Ryo Hisada, Michihito Kono, Yuichiro Fujieda, Tatsuya Atsumi, Masaru Kato   +8 more
doaj   +1 more source

Usefulness of anti -CCP antibodies in rheumatic diseases in Indian patients [PDF]

Indian Journal of Medical Sciences, 2009
The usefulness of anti-cyclic citrullinated peptide antibodies (anti-CCP antibodies) to identify rheumatic arthritis (RA) from other rheumatic diseases presenting with joint pain is not well studied.We aimed to determine the sensitivity and specificity of anti-CCP antibodies in Indian RA patients with respect to non-RA rheumatic diseases and to study ...
Gupta, R., Thabah, M., Aneja, R., Kumar, A., Varghese, T., Chandrasenan, P.J.   +5 more
openaire   +2 more sources

Anti-citrullinated protein antibodies are associated with osteopenia but not with pain at diagnosis of rheumatoid arthritis: data from the BARFOT cohort

Arthritis Research & Therapy, 2019
Background Anti-citrullinated protein antibodies (ACPA) have been suggested to have a potential role in both bone loss and pain in rheumatoid arthritis (RA), based on studies in vitro and in animal models.
Ingiäld Hafström, Sofia Ajeganova, Kristina Forslind, Björn Svensson   +3 more
doaj   +1 more source

Autoanticorpos na artrite reumatoide inicial: coorte Brasília - resultados de uma análise seriada de três anos Autoantibodies in early rheumatoid arthritis: Brasília cohort - results of a three-year serial analysis

Revista Brasileira de Reumatologia, 2011
O valor diagnóstico e prognóstico da análise seriada dos anticorpos como fator reumatoide (FR), anticorpos antipeptídeos citrulinados cíclicos (anti-CCP) e antivimentina citrulinada (anti-Sa) não está definido nos pacientes com artrite reumatoide inicial
Licia Maria Henrique da Mota, Leopoldo Luiz dos Santos Neto, Ivânio Alves Pereira, Rufus Burlingame, Henri A Ménard, Ieda Maria Magalhães Laurindo   +5 more
doaj   +1 more source

Performance of Anticyclic Citrullinated Peptide Antibodies versus Rheumatoid Factor in diagnosis of Rheumatoid Arthritis

Diyala Journal of Medicine, 2019
The aim of this study was to evaluate the performance of anti-cyclic citrullinated peptide antibodies (anti-ccp) versus Rheumatoid Factor (RF) in the diagnosis of rheumatoid arthritis in serum sample of patients with clinical manifestation of arthritis ...
Ali Ibrahim Ali , Mohammed Jasim
doaj   +2 more sources

Comparative Evaluation of Rheumatoid Factor and Anti-CCP Antibody Tests as Diagnostic Markers for Rheumatoid Arthritis: A Cross-sectional Study from a Tertiary Care Centre in Dehradun, Uttarakhand, India [PDF]

National Journal of Laboratory Medicine
Introduction: Rheumatoid Arthritis (RA) is a chronic autoimmune disease with a global prevalence of approximately 1%. It is characterised by persistent joint inflammation and the production of multiple autoantibodies, leading to joint destruction ...
Yogita Rawat, Arti Negi, Pavneesh Kumar, Nidhi Negi, Nidhi Rana, Shalabh Jauhari   +5 more
doaj   +1 more source

Diagnostic utility of Anti-cyclic Citrullinated Peptide Antibodies for Very Early Rheumatoid Arthritis [PDF]

National Journal of Laboratory Medicine, 2014
Background and Objectives: Rheumatoid arthritis (RA) is a systemic autoimmune disorder characterized by widespread joint inflammation with synovial hyperplasia. The most well known diagnostic marker is rheumatoid factor (RF).However; RF is not a good
Sucilathangam G, Anna T, Velvizhi G
doaj   +1 more source

The influence of polygenic risk scores on heritability of anti-CCP level in RA [PDF]

Genes & Immunity, 2014
The objective of this study was to study genetic factors that influence quantitative anticyclic citrullinated peptide (anti-CCP) antibody levels in RA patients. We carried out a genome-wide association study (GWAS) meta-analysis using 1975 anti-CCP+ RA patients from three large cohorts, the Brigham Rheumatoid Arthritis Sequential Study (BRASS), North ...
Cui, Jing, Lee, Yvonne Claire, Weinblatt, Michael, Coblyn, Jonathan, Shadick, Nancy, Karlson, Elizabeth, Taylor, Kimberly E., Källberg, Henrik, Klareskog, Lars, Criswell, Lindsey A., Gregersen, Peter K., Plenge, Robert M.   +11 more
openaire   +4 more sources

Anti-CCP-positive patients with RA have a higher 10-year probability of fracture evaluated by FRAX®: a registry study of RA with osteoporosis/fracture

Arthritis Research & Therapy, 2018
Background Positive anticyclic citrullinated peptide (anti-CCP+) is associated with bone loss in patients with rheumatoid arthritis (RA). However, whether overall positivity or specific levels of anti-CCP are associated with prevalent fracture or a 10 ...
Tien-Tsai Cheng, Shan-Fu Yu, Fu-Mei Su, Yin-Chou Chen, Ben Yu-Jih Su, Wen-Chan Chiu, Chung-Yuan Hsu, Jia-Feng Chen, Chi-Hua Ko, Han-Ming Lai   +9 more
doaj   +1 more source