Results 61 to 70 of about 1,980,019 (202)

Inferring Rheumatoid Arthritis Disease Activity Status From the Electronic Health Records Across Health Systems

Arthritis &Rheumatology, EarlyView.
Objective Disease activity plays a central role in rheumatoid arthritis (RA) clinical studies. The inconsistent availability of data on disease activity in real‐world electronic health records (EHRs) data has limited the ability to generate real‐world evidence (RWE).
David Cheng, Xuan Wang, Gregory C. McDermott, Jennifer S. Hanberg, Zoe Love, Katherine Zhong, Mary Jeffway, Jue Hou, Vidul Panickan, Rahul Sangar, Ying Qi, Connor Melley, Lauren Costa, Dakota Feil, Rachael Matty, Dana Weisenfeld, Abisayo Animashaun, Aimee Schreiner, Sara Morini, Lauren Rusnak, Andrew Cagan, Misti Paudel, J. Michael Gaziano, Brian Sauer, Michael Weinblatt, Joshua Baker, Bryant England, Yuk‐Lam Ho, Kelly Cho, Paul Monach, Grant W. Cannon, Nancy Shadick, Ted R. Mikuls, Tianxi Cai, Katherine P. Liao   +34 more
wiley   +1 more source

Correlation between Anti-CCP Titer and Body Mass Index Score in Rheumatoid Arthritis Patients in Cipto Mangunkusumo Hospital

Indonesian Journal of Rheumatology, 2018
Background: Rheumatoid Arthritis (RA) is a chronic systemic inflammation that attacks and damages joints of upper and lower extremities. RA causes morbidity and disability, hence, affects the quality of life.
Harry Isbagio, Khadijah Fitriah
doaj   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated With Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, EarlyView.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA) and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serologic markers. Methods We analyzed serum and plasma from three cohorts: presymptomatic individuals who later developed RA ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

Bispecific antibodies (BsAb) and anti-CCP assay in mixing tests.

, 2013
(A) One anti-CCP-positive but BsAb-negative serum (#32) was mixed with different dilutions of one RF predominant serum (#3); concentrations of BsAb and anti-CCP in the mixtures were determined.
Jinming Li (128865), Wei Wang (17594)
core   +1 more source

Increased Plasma Microbial tDR‐1 in At‐Risk Individuals Is Associated With Decreased Conversion to Clinical Rheumatoid Arthritis and Reduces an In Vitro Macrophage Type 1 Interferon Response

Arthritis &Rheumatology, EarlyView.
Objective Microbial small RNAs can regulate human genes. Higher plasma concentrations of microbial transfer RNA (tRNA)‐derived RNA‐1 (tDR‐1) were previously associated with lower rheumatoid arthritis (RA) disease activity. This study examined whether tDR‐1 concentrations differ in anticyclic citrullinated peptide‐3 positive (CCP3+) at‐risk individuals (
Anastasiia Phothisane, Tulsi K. Joishy, Carolina Ramirez‐Becerra, Qiong Wu, Jennifer Seifert, Marie L. Feser, Jill M. Norris, M. Kristen Demoruelle, LauraKay Moss, Kevin D. Deane, V. Michael Holers, Michelle J. Ormseth   +11 more
wiley   +1 more source

Anti-cyclic citrullinated peptide antibody titers decrease in rheumatoid arthritis patients treated with tocilizumab: A pilot study [PDF]

, 2019
Objectives: To analyze the effects of tocilizumab on peripheral B-cell subpopulation and its ability to produce anti-cyclic citrullinated peptide (CCP) antibody in patients with rheumatoid arthritis (RA).
Toshiyuki Bohgaki (222986), Yasuda, Shinsuke, Masaru Kato (1298340), Miho Suzuki (207444), Yoshihiro Matsumoto (31279), Atsushi Noguchi (2986758), Ryo Hisada (6494081), Oku, Kenji, Tatsuya Atsumi (186298), Kenji Oku (2986761), Atsumi, Tatsuya, Kato, Masaru, Hisada, Ryo, Matsumoto, Yoshihiro, Bohgaki, Toshiyuki, Shinsuke Yasuda (2986755), Noguchi, Atsushi, Suzuki, Miho   +17 more
core   +1 more source

Anti–Carbamylated Fibrinogen Autoantibodies of IgG and IgA Isotypes Contribute to a Better Prognostic Stratification in Very Early Rheumatoid Arthritis: Data From the French National ESPOIR Cohort

Arthritis &Rheumatology, EarlyView.
Objective The aim of this study was to investigate the prevalence and longitudinal evolution of anti–carbamylated fibrinogen antibodies (ACa‐Fib) of IgG and IgA isotypes in early rheumatoid arthritis (RA) and determine whether these antibodies provide additional diagnostic and prognostic information beyond anti–cyclic citrullinated peptide (anti‐CCP ...
Pauline Brevet, Olivia Guérin, Léna Le Goaréguer, Élisa Halbourg, Marie‐Laure Golinski, Sophie Candon, Olivier Boyer, Thierry Lequerré, Thierry Schaeverbeke, Valérie Devauchelle‐Pensec, Olivier Vittecoq, Manuel Fréret   +11 more
wiley   +1 more source

The association between systemic inflammation as measured by calprotectin and autoantibody load in rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Background Plasma calprotectin is a marker of neutrophil activity. Its relation to the clinical phenotype and autoantibodies in rheumatoid arthritis (RA) is only partly understood. We therefore aimed to investigate the association between calprotectin and clinical parameters, CRP, ESR, anti‐CCP2 and other anti‐modified protein autoantibodies (AMPAs) in
Caroline Grönwall, Linda Mathsson Alm, Helga Westerlind, Isabel Gehring, Nasim Ghasemzadeh, Niels Steen Krogh, Siri Lillegraven, Espen Haavardsholm, Martina Johannesson, Tore K. Kvien, Johan Rönnelid, Tue Wenzel Kragstrup, Bente Glintborg, Merete Lund Hetland, Hilde Berner Hammer, The Danish Rheumatologic Biobank Study Group, Swedish Rheumatology Quality Register Biobank Study Group(SRQb), Johan Askling, Oliver Hendricks, Estrid Høgdall, Dorte Vendelbo Jensen, Heidi Lausten Munk, Jens Kristian Pedersen, Torkell Ellingsen, Anne Gitte Loft, Ellen‐Margrethe Hauge, Salome Kristensen, Lene Dreyer, Asta Linauskas, Søren Jacobsen, Carl Turesson, Solbritt Rantapää Dahlqvist, Lena Björkman, Alf Kastbom, Eva Baecklund   +34 more
wiley   +1 more source

Anti-cyclic citrullinated peptide antibodies – a role in rheumatoid arthritis and the possibility of seroconversion: A focus on abatacept

Современная ревматология, 2017
The detection of anti-cyclic citrullinated peptide (anti-CCP) antibodies plays a diagnostic and statistical predictive role in rheumatoid arthritis (RA).
N. V. Chichasova
doaj   +1 more source

Cartilage Oligomeric Matrix Protein Associates Differentially with Erosions and Synovitis and Has a Different Temporal Course in Cyclic Citrullinated Peptide Antibody (Anti-CCP)-positive versus Anti-CCP-negative Early Rheumatoid Arthritis [PDF]

, 2011
Objective.Cyclic citrullinated peptide antibody (anti-CCP)-positive and anti-CCP-negative rheumatoid arthritis (RA) have been suggested as 2 distinctive disease subsets with respect to disease activity and prognosis. Previously, we proposed that anti-CCP
Jacobsen, Søren, Østergaard, Mikkel, Junker, Michael Peter, Lindegaard, Hanne, Ejbjerg, Bo Jannik, JENS K. PEDERSEN, Christensen, Anne F, Pedersen, Jens K, Svendsen, Anders, HENRIK SKJØDT, Pedersen, Jens K; id_orcid, Ostergaard, Mikkel, Pødenphant, Jan, Hansen, Ib, ULRIK TARP, SØREN JACOBSEN, ANDERS SVENDSEN, Junker, Peter, Hansen, Ib Tønder, TINE LOTTENBURGER, HANNE LINDEGAARD, KIM HØRSLEV-PETERSEN, BO EJBJERG, Andersen, Lis S, Ejbjerg, Bo, Skjødt, Henrik, JAN PØDENPHANT, PETER JUNKER, Ellingsen, Torkell Juulsgaad, Hetland, Merete Lund, Hørslev-Petersen, Kim, IB HANSEN, Ellingsen, Torkell Juulsgaad; id_orcid, Stengaard-Pedersen, Kristian, KRISTIAN STENGAARD-PEDERSEN, Lauridsen, Ulrik Birk, MERETE L. HETLAND, Lottenburger, Tine, ULRIK B. LAURIDSEN, Svendsen, Anders; id_orcid, ANNE F. CHRISTENSEN, MIKKEL ØSTERGAARD, Andersen, Lis Abildgaard, LIS S. ANDERSEN, Hetland, Merete L, TORKELL ELLINGSEN, Tarp, Ulrik, Lauridsen, Ulrik B   +47 more
core   +1 more source