Results 71 to 80 of about 1,980,019 (202)

Outcomes of Tapering Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs in Rheumatoid Arthritis: A Multicenter Randomized Noninferiority Trial

Arthritis &Rheumatology, EarlyView.
Objective Evidence supporting tapering of biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) in patients with rheumatoid arthritis (RA) with sustained low disease activity (LDA) remains limited. We evaluated the efficacy and safety of a structured b/tsDMARD‐tapering strategy in patients with RA who had achieved sustained ...
Dong‐Jin Park, Sung‐Eun Choi, Ji‐Hyoun Kang, Jung‐Yoon Choe, Hye‐Soon Lee, So‐Young Bang, Yun‐Hong Cheon, Sang‐Il Lee, Mingyo Kim, Yoon‐Kyoung Sung, Soo‐Kyung Cho, Jae Hyun Jung, Sung Hae Chang, Sung Won Lee, Yeon‐Ah Lee, Seung‐Geun Lee, Hyun‐Sook Kim, Seung‐Ki Kwok, Seung‐Cheol Shim, Shin‐Seok Lee   +19 more
wiley   +1 more source

Anti-CCP antibodies: A Better Diagnostic Tool for Rheumatoid Arthritis [PDF]

, 2009
Introduction: Rheumatoid factors are currently used in the diagnosis of rheumatoid arthritis and constitute one of the classification criteria proposed by the American College of Rheumatology. However, rheumatoid factor positivity shows low diagnostic
Hussin, Che Maraina Che
core   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Anti-CCP antibodies are not associated with familial Mediterranean fever in childhood [PDF]

, 2013
Objective. Anticyclic citrullinated peptide antibodies (anti-CCP) testing is useful in the diagnosis of rheumatoid arthritis (RA) with high specificity. Arthritis is a very common clinical manifestation in children with familial Mediterranean fever (FMF).
Usta M., Bercem G., Onur H., Aral H., Kasapcopur Ö., Arica V.   +5 more
core   +2 more sources

Is anti-cyclic citrullinated peptide antibody a good value biomarker for alzheimer disease?

International Journal of Preventive Medicine, 2013
Background: Alzheimer′s disease (AD) is one of the most important neurodegenerative disorder. Anti-cyclic citrullinated peptide (anti-CCP) may all be involved in the development of vascular disease such as AD.
Rokhsareh Meamar, Gholamreza Askari, Majid Ghasemi, Mohammad Reza Aghaye Ghazvini, Sahar Vesal, Mostafa Sharifkhah, Nazanin Alaei Faradonbeh   +6 more
doaj  

The Influence of Polygenic Risk Scores on Heritability of Anti-CCP Level in RA [PDF]

, 2014
Objective: To study genetic factors that influence quantitative anti-cyclic citrullinated peptide (anti-CCP) antibody levels in RA patients. Methods: We carried out a genome wide association study (GWAS) meta-analysis using 1,975 anti-CCP+ RA patients ...
Lee, Yvonne Claire, Klareskog, Lars, Kallberg, H, Taylor, Kimberly E., Plenge, Robert M., Klareskog, L., Shadick, Nancy, Taylor, KE, Klareskog, L,, Coblyn, Jonathan, Shadick, NA, Kallberg, H., Gregersen, PK, Taylor, K. E., Cui, Jing, Weinblatt, ME, Gregersen, Peter K., Criswell, L. A., +2 additional authors, Karlson, E. W., Cui, J, Cui, J., Coblyn, J. S., Weinblatt, M. E., Criswell, LA, Gregersen, P. K., Källberg, Henrik, Lee, Y. C., Weinblatt, Michael, Karlson, Elizabeth, Criswell, Lindsey A., Lee, YC, Coblyn, JS   +32 more
core   +1 more source

Chemistry Underlying the Behavior of Food and Agricultural Components During Industrial Manufacturing Processes and Its Implications in Quality Assurance, Food Quality, and Food Safety Management: A Systematic Review

Food Safety and Health, EarlyView.
Industrial manufacturing processes have transformative effects on the components of food matrix. These transformations in food matrix and components have direct implications for quality assurance (QA), food quality (e.g., nutritional profile and texture), and food safety management (e.g., pathogen control and toxin mitigation). ABSTRACT This systematic
Chinaza Godswill Awuchi
wiley   +1 more source

The Correlation Value of DAS28 with Anti-CCP Titer on Rheumatoid Arthritis Patients in Cipto Mangunkusumo Hospital in 2012-2016

Indonesian Journal of Rheumatology, 2018
Background: Rheumatoid Arthritis (RA) is one of the diseases associated with the immune system which causes joint damage and effect to the quality of patient’s life. DAS28 CRP value describes RA disease activity.
Harry Isbagio, Deka Yuli Fadillah
doaj   +1 more source

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue, Daniele Carchidi, Philipp Schmucker, Roland Seiler, Bernhard Kiss, Catarina Macedo‐Silva, Marianna Kruithof‐de Julio   +6 more
wiley   +1 more source

Antikörper gegen cyclische citrullinierte Peptide (anti-CCP):Wertigkeit eines Markers im Verlauf der Rheumatoiden Arthritis

, 2008
Anti-CCP haben sich in der Diagnostik der RA als wichtiges Hilfsmittel etabliert. Wir untersuchten, ob die Bestimmung von anti-CCP auch eine Bedeutung in der Verlaufsbeurteilung der RA hat. Dazu analysierten wir 100 Patienten mit RA. 84 von 100 Patienten
Butenschön, A. (Annkathrin)
core   +2 more sources