Results 131 to 140 of about 67,371 (260)

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

open access: yesDrug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda   +9 more
wiley   +1 more source

Spatial constraints determine the spread of plasmid-encoded antibiotic resistance between bacterial colonies. [PDF]

open access: yesmSystems
Ramoneda J   +7 more
europepmc   +1 more source

Simultaneous Detection of Steroid Esters and Multi‐Class Substances in Dried Blood Spots by LC‐HRMS/MS From a Single Spot for Human Doping Control

open access: yesDrug Testing and Analysis, EarlyView.
A validated LC‐HRMS/MS method enabled, for the first time, the comprehensive detection of steroid esters and multi‐class menu substances from a single dried blood spot. Following extraction, the resulting extract is split into two aliquots, reducing sample consumption and simplifying the analytical workflow.
Panagiotis Sakellariou   +4 more
wiley   +1 more source

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard   +3 more
wiley   +1 more source

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

open access: yesDevelopmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble   +2 more
wiley   +1 more source

Near‐Infrared Light‐Driven Photocatalysis: From Advanced Light‐Harvesting Architectures to Rational Reactor Design

open access: yesEcoEnergy, EarlyView.
This review systematically elucidates the regulatory strategies for NIR light, encompassing macroscopic mechanisms such as band engineering, localized surface plasmon resonance (LSPR), upconversion luminescence, and photosensitizer molecules. Furthermore, it provides an in‐depth discussion on their cutting‐edge applications in energy conversion (e.g ...
Huijuan Wang   +8 more
wiley   +1 more source

Evaluation, Management, and Return-To-Sport Guidelines for Cervical Spine Injuries in Athletes: A Narrative Review. [PDF]

open access: yesGlobal Spine J
Batrash F   +12 more
europepmc   +1 more source

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