Results 151 to 160 of about 67,371 (260)

Hepatocellular carcinoma-cholangiocarcinoma collision tumor with excellent therapeutic response: a case report and literature review. [PDF]

Discov Oncol
Sun Z, Wang Y, Peng C, Tan Z.
europepmc   +1 more source

Dissecting the angiogenic mechanism of pachychoroid polypoidal choroidal vasculopathy

iMeta, EarlyView.
A prognosis‐oriented classification system was established to distinguish Pachy PCV from Non‐pachy PCV using a large multicenter dataset. Comparative plasma multi‐omics profiling of Pachy PCV, Non‐pachy PCV, and normal controls revealed unique upregulation of the fluid shear stress and atherosclerosis (FSS‐AS) and HIF‐1 signaling pathways in Pachy PCV.
Xinyu Zhao, Tiantian Cheng, Wenfei Zhang, Xingwang Gu, Qing Zhao, Yaning Chen, Lihui Meng, Jiaqi Zhang, Bintao Qiu, Lili Li, Shiyu Cheng, Zicheng Wang, Chuting Wang, Yuelin Wang, Zuyi Yang, Zhengming Shi, Ye Guo, Shengzhi Liu, Youxin Chen   +18 more
wiley   +1 more source

Unveiling a flip-over retention mechanism in the gas-phase Cl^- + (CH₃)₃CI S_N2 reaction. [PDF]

Nat Commun
Lu X, Meyer J, Li L, Carrascosa E, Bastian B, Michaelsen T, Fu B, Zhang DH, Wester R.   +8 more
europepmc   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Deep Reinforcement Learning for Anti-Jamming Dynamic Spectrum Access: A Bootstrap Ensemble Approach with Echo State Network and Idle-Ratio Change Detection. [PDF]

Sensors (Basel)
Jiang H, Bian X, Li M.
europepmc   +1 more source

Controlling Growth of Ultrasmall Sub‐10 nm Silver Nanoparticles From Cotinus coggygria Scop. Extract and Evaluation of Its In Vitro Anti‐Breast Cancer, Antioxidant and Antimicrobial Activity

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study highlights the potential use of Cotinus coggygria Scop. plant extract in a single‐step synthesis of biocompatible and ultrasmall AgNPs for in vitro applications. Herein, microscopic analyses revealed that AgNP exposure did not induce appreciable morphological changes in CRL‐4010 cells, whereas MCF‐7 and MDA‐MB‐231 cells exhibited ...
Ümran Ünüvar, Tuğba Nur Aslan, Suray Pehlivanoğlu, Kübra Ece Coşkuner   +3 more
wiley   +1 more source

Multisensor Localization and Risk-Aware Navigation for Underwater Robots in Turbid and Confined Inland Waters: A Review. [PDF]

Sensors (Basel)
Tang R, Zang Q, Zhang Y, Wu Y, Yang J, Tang Z.   +5 more
europepmc   +1 more source

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

Correlations and Kappa Distributions: Numerical Experiment with 3D Collisions and Debye-like Shielding. [PDF]

Entropy (Basel)
McComas DJ, Livadiotis G, Sarlis N.
europepmc   +1 more source

A Semi‐Automated Microfluidic Platform Employing Machine Learning Analysis to Study Adhesion Kinetics in Acute Myeloid Leukemia

Microscopy Research and Technique, EarlyView.
We have developed a semi‐automated shear flow platform using bright‐field optics and a machine‐learning analysis algorithm to dissect tumor‐microenvironment interactions. The algorithm quantifies the extent of adhesion at the single‐cell level and delivers consistent results within minutes instead of hours, facilitating high‐throughput analysis ...
Driti Ashok, Dennis Raith, Gabriel Kalweit, Maria Kalweit, Anusha Klett, Justus Duyster, Jonas Bermeitinger, Tanja Nicole Hartmann   +7 more
wiley   +1 more source