Results 151 to 160 of about 64,578 (259)

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Autonomous UAV Landing and Collision Avoidance System for Unknown Terrain Utilizing Depth Camera with Actively Actuated Gimbal. [PDF]

Sensors (Basel)
Łuczak P, Granosik G.
europepmc   +1 more source

Pharmacokinetics and Acute Safety Evaluation of Tryptanthrin, A Bioactive Constituent of Indigo naturalis, Following Intravenous Administration in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The use of Indigo naturalis in treating inflammatory diseases is clinically restricted by severe adverse events, including pulmonary arterial hypertension and hepatotoxicity. Tryptanthrin, a major indoloquinazoline alkaloid of Indigo naturalis, exhibits potent anti‐inflammatory activity; however, its specific safety profile relative to the ...
Hyung Jin Kim, Gabsik Yang, Jun Ho Lee
wiley   +1 more source

Anti interference and fault tolerant control of UAVs integrating residual based diagnosis disturbance estimation with counter drone strategies. [PDF]

Sci Rep
Xie Z, Long Y.
europepmc   +1 more source

Controlling Growth of Ultrasmall Sub‐10 nm Silver Nanoparticles From Cotinus coggygria Scop. Extract and Evaluation of Its In Vitro Anti‐Breast Cancer, Antioxidant and Antimicrobial Activity

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study highlights the potential use of Cotinus coggygria Scop. plant extract in a single‐step synthesis of biocompatible and ultrasmall AgNPs for in vitro applications. Herein, microscopic analyses revealed that AgNP exposure did not induce appreciable morphological changes in CRL‐4010 cells, whereas MCF‐7 and MDA‐MB‐231 cells exhibited ...
Ümran Ünüvar, Tuğba Nur Aslan, Suray Pehlivanoğlu, Kübra Ece Coşkuner   +3 more
wiley   +1 more source

Effect of Humidity on Ionisation and Ion Chemistry in Active-Capillary Dielectric Barrier Discharge Ionisation. [PDF]

Rapid Commun Mass Spectrom
Polášek M, Španěl P, Dryahina K.
europepmc   +1 more source

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

An intelligent SCADA-integrated deep learning framework for bird-safe offshore wind farm operation. [PDF]

Sci Rep
Sultan YA, Sameh A, Gamel SA.
europepmc   +1 more source

Testing and Extending the Minority Stress Model Among Jewish College Students: A Mixed Methods Study

Journal of Counseling &Development, EarlyView.
ABSTRACT Antisemitic incidents have increased on US college campuses, yet psychological frameworks for understanding Jewish experiences are limited. In this study, we used mixed methods to apply the minority stress model (MSM) to Jewish students at a large Midwestern university.
Jacob Schachter, Alex A. Ajayi
wiley   +1 more source

Specific design strategies for elderly-friendly residential spaces in nursing homes: an integrated model approach based on empathy map-KANO-AHP-PUGH. [PDF]

Front Psychol
Jintao Z, Weisong G, Ning Z, Lei W.
europepmc   +1 more source