Results 61 to 70 of about 67,371 (260)

High‐Entropy Engineering and External Magnetic Field Modulation Synergistically Enhance the H2S Sensing Performance of Rare‐Earth Perovskite Ferrites

open access: yesAdvanced Science, EarlyView.
A novel high‐entropy perovskite oxide, (Gd0.2Tb0.2Dy0.2Ho0.2Er0.2)FeO3, was successfully synthesized for advanced hydrogen sulfide gas detection. By synergistically coupling high‐entropy‐induced local lattice distortion with weak magnetic field modulation, the tailored material generates abundant active sites. This innovative dual strategy dramatically
Yunfei Wang   +7 more
wiley   +1 more source

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

open access: yesAdvanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li   +11 more
wiley   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

Efficient Cholesteric Liquid Crystal Waveguide Polarizing Splitters for High‐Sensitivity Chip‐Scale Atomic Magnetometry

open access: yesAdvanced Science, EarlyView.
An integrated polarimetry architecture based on a cholesteric liquid crystal waveguide polarization splitter overcomes the volumetric bottleneck in chip‐scale atomic magnetometers. By leveraging Bragg‐selective reflection and total‐internal‐reflection‐induced helicity inversion, this ultrathin device enables efficient circular polarization splitting ...
Zhibo Cui   +9 more
wiley   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

open access: yesAdvanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan   +9 more
wiley   +1 more source

Precisely Regulating 2.45 s Pure Blue Room‐Temperature Phosphorescence via Supramolecular Coordination

open access: yesAdvanced Science, EarlyView.
Herein, a pure deep blue room‐temperature phosphorescence (415 nm) with lifetime up to 2.45 s is successfully achieved by a covalently crosslinking purely organic material based on boric acid (BA) and 3,5‐dicarboxyphenylboronic acid (BOP) through a simple dehydration reaction, which can be adjusted precisely by supramolecular coordination with ...
Jun Wang   +5 more
wiley   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

open access: yesAdvanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai   +7 more
wiley   +1 more source

Photoactivation‐Enabled Tunable Room‐Temperature Phosphorescence and Thermally Activated Delayed Fluorescence in Crystalline Materials

open access: yesAdvanced Science, EarlyView.
This work is the first to demonstrate the regulation of photoactivated room‐temperature phosphorescence (RTP) and thermally activated delayed fluorescence (TADF) in crystalline materials without any pretreatment. Furthermore, we reveal the underlying mechanisms by uncovering the role of host‐guest energy level alignment, exciton lifetime, crystallinity,
Lisha Zhang   +5 more
wiley   +1 more source

A Dual‐Mode In Situ EV‐miRNA Profiling Platform for Machine‐Learning‐Assisted Gastric Cancer Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
An in situ dual‐mode platform integrates fusogenic liposomes with localized autocatalytic DNA circuits for plasma‐derived extracellular vesicle microRNA analysis. Following membrane fusion, target miRNAs trigger feedback‐assisted LECHA amplification inside intact vesicles, generating fluorescence and electrochemical outputs. Machine learning integrates
Wenbin Li   +15 more
wiley   +1 more source

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