Results 71 to 80 of about 64,578 (259)

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

open access: yesAdvanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang   +7 more
wiley   +1 more source

Experimental Study of the Condenser of an Automotive Air Conditioner with Non-uniform Inlet Air Velocity

open access: yesZhileng xuebao, 2020
The condenser is one of the important components in an automotive air conditioning system. A traditional condenser is designed on the premise that the inlet air volume is evenly distributed.
Liu Yusheng   +5 more
doaj  

Timing-Aware RFID Anti-Collision Protocol to Increase the Tag Identification Rate

open access: yesIEEE Access, 2018
Radio frequency identification (RFID) technology is one of the most popular systems to uniquely identify items by attaching a tag to them. The growing number of tagged items that need to be identified in one reader interrogation area leads to high tag ...
Laura Arjona   +3 more
doaj   +1 more source

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

open access: yesAdvanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg   +16 more
wiley   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Design and Implementation of a Highly Reliable Anti-Collision Mechanism for CPCI Backboard Communication System

open access: yes机车电传动, 2017
A highly reliable and anti-collision mechanism for data communication between master and slave control modules was proposed, and corresponding functional modules on the FPGA were realized, which integrated the CPCI backboard communication and DPRAM ...
LU Qi, ZHOU Xuexun, JIANG Guotao
doaj  

The Sensitivity of Safe Ship Control in Restricted Visibility at Sea [PDF]

open access: yesTransNav, 2012
The structure of safe ship control in collision situations and computer support programmes on base information from the ARPA anti-collision radar system has been presented.
Jozef Lisowski
doaj  

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

open access: yesAdvanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li   +8 more
wiley   +1 more source

Production monitoring and machine tracking in underground mines based on a collision avoidance system: A case study

open access: yesComputer Assisted Methods in Engineering and Science
In the era of Industry 4.0, one of the key challenges facing underground mines is the real-time tracking of both the production process and machinery movements.
Artur Skoczylas   +4 more
doaj   +1 more source

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