Results 51 to 60 of about 564,787 (298)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Specifying the notion of “Institutional anti-crisis management of a region”

Russian Journal of Economics and Law, 2022
Objective: to develop a new approach to the definition of regional anti-crisis management, taking the institutional factors into account.Methods: abstract-logical method is used.
N. Yu. Chehonin
doaj   +1 more source

Essence and economic nature of financial resources of enterprises [PDF]

, 2018
У статті розглянуто різні підходи до визначення сутності поняття "фінансові ресурси", уточнено дефініцію "фінансові ресурси підприємства", визначено критерії класифікації фінансових ресурсів.
Бережна, Юлія Валеріївна, Другов, Олена Сергіївна   +1 more
core  

Peculiarities of anti-crisis management of trade enterprises [PDF]

, 2018
У статті розглядається аналіз сучасного стану торговельної галузі України та порівняння її показників із світовими тенденціями. Досліджено структуру української економіки за різними показниками.
Білоцерківський, Олександр Борисович, Соснов, Ігор Ігорович   +1 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

SYSTEM PROBLEM`S OF BANKRUPT IN RUSSIA

Стратегические решения и риск-менеджмент, 2014
Mechanism of bankrupt procedure Implementation was analyzed, which were identified current system problems, happened by imperfect of law, presented proposals to developing it. The special attention on  protection of the rights of entrepreneurs in case of
S. Е. Кovan, А. N. Ryahovskaya, N. V. Kotsyuba   +2 more
doaj   +1 more source

Conceptual approaches towards interpretation of anti-crisis management economic essence [PDF]

, 2013
Виокремлено концептуальні підходи вітчизняних та зарубіжних авторів до трактування економічної сутності антикризового менеджменту. На підставі проведення ретроспективного аналізу встановлено причини появи та розвитку антикризового менеджменту як одного ...
Manzhos, Svitlana, Манжос, Світлана   +1 more
core  

MANAGEMENT OF ANTI-CRISIS MANAGEMENT OF ENTERPRISES

Market Infrastructure
The article considers different approaches to understanding financial planning, highlights its importance as a tool for reducing financial risks and ensuring the financial stability of the enterprise. Special attention is paid not only to profitability forecasting, but also to factors affecting solvency and capital structure. The article also describes
Olena Smetaniuk, Yuriy Karpinskyi
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

ESSENCE AND COMPONENTS OF INNOVATION POTENTIAL IN THE SYSTEM OF CRISIS MANAGEMENT

Модернизация, инновация, развитие, 2015
The article specifies the concept and composition of innovation potential and off ers the structure of this economic category. The concept of the innovation potential of the company is considered.
N. G. Akulova, A. S. Urusov
doaj