Differences in synovial tissue infiltrates between anti–cyclic citrullinated peptide–positive rheumatoid arthritis and anti–cyclic citrullinated peptide–negative rheumatoid arthritis [PDF]
AbstractObjectiveTo compare synovial tissue infiltrates from patients with anti–cyclic citrullinated peptide (anti‐CCP)–positive rheumatoid arthritis (RA) with those from patients with anti‐CCP–negative RA.MethodsSynovial tissue samples were obtained arthroscopically from the inflamed knee joints of 57 patients with RA (34 of whom were anti‐CCP ...
van Oosterhout M +5 more
openaire +3 more sources
Objective: Patients with chronic hepatitis C virus (HCV) infection may show a variety of rheumatic symptoms and signs. Anti-cyclic citrullinated peptide (anti-CCP) is widely used as as a marker, particularly for rheumatoid arthritis (RA), and may be ...
Ayşe Albayrak +3 more
doaj +1 more source
Detection of Anti-Vimentin Antibodies in Patients with Sarcoidosis
There is a need to further characterize the antibody response to vimentin in relation to its possible involvement in pathogenicity of sarcoidosis and other lung disorders.
Anna Starshinova +7 more
doaj +1 more source
The Association Between Anti-Cyclic Citrullinated Peptide and Anti-Mutated Citrullinated Vimentin and The Extra-articular Manifestations in Patients with Rheumatoid Arthritis [PDF]
Background: Early detection of extra-articular symptoms [ExRA] in RA patients is crucial, and lifesaving. This study examined the relationship between Anti-Cyclic Citrullinated Peptide [Anti-CCP] and Anti-Mutated Citrullinated Vimentin [Anti-MCV ...
Hamdy Eid Khafagy +3 more
doaj +1 more source
Serum Autoantibody Biomarkers for Management of Rheumatoid Arthritis Disease
Rheumatoid arthritis (RA) is a systemic chronic autoimmune inflammatory disease that is characterized by the destruction of bone and production of autoantibodies such as rheumatoid factor (RF) and anticitrullinated protein antibodies (ACPAs).
Esther Sánchez-Tirado +6 more
doaj +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Factors associated with hand joint destruction in Chinese patients with rheumatoid arthritis
Background There have been no previous report of hand joint destruction prevalence in Chinese rheumatoid arthritis (RA) patients. Therefore, the aim of this study was to investigate the prevalence and potential factors of hand joint destruction among RA ...
Lijuan Zhang +8 more
doaj +1 more source
Anti‐cyclic citrullinated peptide antibodies in type 1 autoimmune hepatitis [PDF]
SummaryBackground : Besides the autoantibodies included in the diagnostic criteria of type 1 autoimmune hepatitis, many other autoantibodies have been described in this condition. Recently, antibodies against cyclic citrullinated peptide have been validated as specific diagnostic and prognostic markers of rheumatoid arthritis.Aim : To assess whether ...
M, Fusconi +9 more
openaire +2 more sources
The prevalence of anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritis
OBJECTIVES: To assess the presence of anti-cyclic citrullinated peptide antibodies in a cohort of patients with juvenile idiopathic arthritis. METHODS: Anti-cyclic citrullinated peptide antibodies was tested for with an enzyme linked immunoabsorbent assay (ELISA) in serum samples of patients from the Hospital de Clínicas de Porto Alegre, all less than ...
Sandra H, Machado +4 more
openaire +3 more sources
Anti-cyclic citrullinated peptide revised criteria for the classification of rheumatoid arthritis [PDF]
The classification of rheumatoid arthritis (RA) is increasingly important as new therapies can halt the disease in its early stages. Antibodies to cyclic citrullinated peptides (anti-CCP) are widely used for RA diagnosis, but are not in the 1987 American College of Rheumatology (ACR) Criteria for RA Classification.
K P, Liao +4 more
openaire +2 more sources

