Anti-cyclic citrullinated peptide antibodies in patients with primary Sjögren's syndrome [PDF]
Primary Sjogren’s syndrome (pSS) is an autoimmune late onset disease characterised mainly by sicca symptoms. Lymphocytic infiltrate of the minor salivary glands and the presence of autoantibodies are the hallmarks of disease.1 The spectrum of pSS extends from an organ-specific autoimmune disorder (autoimmune exocrinopathy) to a systemic process that ...
Tobón, G J +2 more
openaire +3 more sources
Objective: To compare the diagnostic utility of laboratory variables, including matrix metalloproteinase-3 (MMP-3), anti-cyclic citrullinated peptide (CCP) antibodies, rheumatoid factor (RF), erythrocyte sedimentation rate (ESR),
O. Shovman +6 more
doaj +1 more source
Serum Autoantibody Biomarkers for Management of Rheumatoid Arthritis Disease
Rheumatoid arthritis (RA) is a systemic chronic autoimmune inflammatory disease that is characterized by the destruction of bone and production of autoantibodies such as rheumatoid factor (RF) and anticitrullinated protein antibodies (ACPAs).
Esther Sánchez-Tirado +6 more
doaj +1 more source
Diagnostic utility of Anti-cyclic Citrullinated Peptide Antibodies for Very Early Rheumatoid Arthritis [PDF]
Background and Objectives: Rheumatoid arthritis (RA) is a systemic autoimmune disorder characterized by widespread joint inflammation with synovial hyperplasia. The most well known diagnostic marker is rheumatoid factor (RF).However; RF is not a good
Sucilathangam G, Anna T, Velvizhi G
doaj +1 more source
Expression and diagnostic utility of anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritis [PDF]
Background: Juvenile idiopathic arthritis (JIA) is a clinically heterogeneous group of arthritis occurring in children. Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been recently included in the revised diagnostic criteria for adult onset
Afify, MF, El Laban, AS, Sayed, AO
core +1 more source
The diagnostic value of anti-cyclic citrullinated peptide antibodies, adenosine deaminase activity and other potential biomarkers for predicting and monitoring rheumatoid arthritis [PDF]
The aim of this study was to investigate the presence of anti-cyclic citrullinated peptide antibodies (anti- CCP2) in RA and non-RA patients and to evaluate the combination of these auto-antibodies with some other markers such as RF and CRP.
Mehanović-Nikolić Jasminka +6 more
doaj
Anti-Cyclic Citrullinated Peptide Antibodies in Rheumatoid Arthritis and Behcet's Disease
Rheumatoid arthritis (RA) is associated with progressive joint destruction and disability. Early diagnosis of RA is important, since early and aggressive treatments lead to a better outcome. Circulating autoantibodies are a serological hallmark of systemic rheumatic diseases.
Koca, Suleyman Serdar +4 more
openaire +3 more sources
Development of synthetic anti‐cyclic citrullinated peptide antibody and its arthritogenic role [PDF]
This study was undertaken to develop a novel anti‐citrullinated peptide antibody (ACPA) and to investigate its arthritogenicity in a collagen‐induced arthritis (CIA) model. The novel ACPA, 12G1, was developed by injecting cyclic citrullinated antigen in mice and subsequently hybridizing the B cells producing citrullinated peptide‐specific antibodies ...
Kim, Youngkyun +6 more
openaire +3 more sources
ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODIES IN RHEUMATOID ARTHRITIS PATIENTS
Objective: To detect the anti cyclic citrullinated peptide (Anti-CCP) antibody in rheumatoid arthritis (RA) patients to determine its diagnostic value in Pakistani patients. Study Design: Cross sectional study.
Amer Fakhr +4 more
doaj +2 more sources
Objective Anti-citrullinated protein antibodies (ACPA) and anti-cyclic citrullinated peptide (anti-CCP) antibodies are a hallmark of rheumatoid arthritis and are believed to play a role in disease pathogenesis.
Ioan-Facsinay, A. +8 more
core +1 more source

