Results 81 to 90 of about 3,095,599 (228)

The Association Between Anti-Cyclic Citrullinated Peptide and Anti-Mutated Citrullinated Vimentin and The Extra-articular Manifestations in Patients with Rheumatoid Arthritis [PDF]

International Journal of Medical Arts
Background: Early detection of extra-articular symptoms [ExRA] in RA patients is crucial, and lifesaving. This study examined the relationship between Anti-Cyclic Citrullinated Peptide [Anti-CCP] and Anti-Mutated Citrullinated Vimentin [Anti-MCV ...
Hamdy Eid Khafagy, Hisham El-Desouky Abd El-Wahab, Tarek Mostafa Omran, Tarek Mohammad Abd El-Aziz   +3 more
doaj   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

Benefit of early treatment in inflammatory polyarthritis patients with anti-cyclic citrullinated peptide antibodies versus those without antibodies [PDF]

, 2010
Objective To compare the clinical utility of anti–cyclic citrullinated peptide (anti-CCP) antibodies and rheumatoid factor (RF) testing in predicting both functional outcome and response to treatment in early inflammatory polyarthritis (IP) patients ...
Bunn, Diane K., Bunn, Diane, Barton, Anne; id_orcid, Plant, Darren, Barton, Anne, Farragher, Tracey M., Plant, D, Lunt, M, Symmons, Deborah P. M., Bunn, DK, Symmons, Deborah P M, Farragher, TM, Barton, A, Lunt, Mark, Plant, Darren; id_orcid, Farragher, Tracey M.; id_orcid, Symmons, DPM, Lunt, Mark; id_orcid   +17 more
core   +1 more source

Onset of polyarticular juvenile idiopathic arthritis with both anti-cyclic citrullinated peptide antibodies and rheumatoid factor in a 3-year-old girl

Pediatric Rheumatology Online Journal, 2012
This report describes 3 year old girl with the unusual presentation of polyarticular juvenile idiopathic arthritis (JIA) with anti-cyclic citrullinated peptide (anti-CCP) antibodies and a positive rheumatoid factor (RF).
Yasui Kozo, Sakata Sonoko, Ochi Hideaki, Itamura Shinji, Hirai Kenta, Takenaka Mieko, Mitani Osamu, Ogawa Kazunori, Iyoda Kuniaki   +8 more
doaj   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source

Anti-citrullinated protein antibodies as biomarkers in rheumatoid arthritis

, 2023
Introduction: The serological biomarker anti-citrullinated protein antibodies (ACPAs) may have several functions but is especially important for the diagnosis of rheumatoid arthritis (RA) along with clinical symptoms.
Houen, Gunnar, Gunnar Houen, Nicole Hartwig Trier, Trier, Nicole Hartwig   +3 more
core   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Plotting the Articular Disease Impact of Juvenile Idiopathic Arthritis: Discernments into Clinical Phenotypes and Demographic Tide in a Pakistani Cohort

Pakistan Armed Forces Medical Journal
Objective: To investigate into the pattern of joint engagement along with the laboratory markers in Juvenile Idiopathic Arthritis (JIA) amongst the Pakistani cohort. Study Design: Cross-sectional study.
Annam Javed, Amer Fakhar, Sadia Ali, Amina Khurshid, Usama Zahid   +4 more
doaj   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source

Biosensor analysis of anti citrullinated protein/peptide antibodies (ACPA) affinity

, 2014
Anti-citrullinated protein/peptide antibodies (ACPAs) are detected in rheumatoid arthritis (RA) sera and because of their strict association with the disease are considered marker antibodies, probably endowed with pathogenic potential.
Rossi G, MIGLIORINI, PAOLA, PRATESI, FEDERICO, Real Fernandez F, Rovero P, PANZA, FILOMENA   +5 more
core   +1 more source