Results 61 to 70 of about 7,850 (302)

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

open access: yesAdvanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian   +13 more
wiley   +1 more source

Post Tonsillectomy Nausea and Vomiting: Role of Single Intravenous Dose of Dexamethasone

open access: yesGomal Journal of Medical Sciences, 2013
Background: Tonsillectomy is the commonest ENT surgical procedure. The common postoperative morbidities associated with tonsillectomy are nausea, vomiting, pain and bleeding.
Muhammad Ismail Khan   +3 more
doaj  

Migraine management for the otolaryngologist

open access: yesLaryngoscope Investigative Otolaryngology, 2023
Objective To characterize migraine pathophysiology, presentation, and current treatment strategies, specifically in regard to vestibulocochlear manifestations of migraine. Methods Narrative review of available literature. Results Migraine disorder can be
Kaitlyn A. Brooks   +3 more
doaj   +1 more source

Wild mushroom exposures in Kansas, 2013–2018

open access: yesToxicology Communications, 2021
Background Mushrooms exposures are uncommon, difficult to characterize, and occasionally cause serious morbidity and mortality. We describe mushroom exposures reported to the Kansas Poison Control Center (KSPCC).Methods We queried the KSPCC database for ...
Sam Wagner   +4 more
doaj   +1 more source

Cluster randomisation or randomised consent as an appropriate methodology for trials in palliative care: a feasibility study [ISRCTN60243484] [PDF]

open access: yes, 2004
BACKGROUND: Although guidelines for the care of the dying patient exist the evidence base to support the guidelines is poor. Some of the factors contributing to this include failure to recruit to trials, protective healthcare professionals and subsequent
Etchells, E   +4 more
core   +1 more source

Anti-Emetic Efficacy of Tropisetron and Metoclopramide

open access: yesJournal of International Medical Research, 1996
Post-operative vomiting, especially in ambulatory surgical patients, remains a troublesome problem. This placebo-controlled, randomized, prospective double-blind trial was designed to evaluate the efficacy of two prophylactic anti-emetic regimens on post-operative vomiting in 1-day thyroid surgery.
Kutlay, O   +4 more
openaire   +3 more sources

Biomimetic Polymerization of Tellurocysteine: Breaking the Natural Amino Acid Radioprotection Limitation

open access: yesAdvanced Science, EarlyView.
Inspired by natural amino acid polymer‐melanin systems, this study strategically incorporated tellurocysteine to develop advanced radiation‐shielding materials. This approach transformed the primary interaction mechanism between melanin‐based materials and incident photons from Compton scattering to the photoelectric effect. Tellurocysteine‐polymerized
Wei Chen   +6 more
wiley   +1 more source

Safety and efficacy of peripheral nerve blocks to treat refractory headaches after aneurysmal subarachnoid hemorrhage – A pilot observational study

open access: yesFrontiers in Neurology, 2023
ObjectivesHeadache after aneurysmal subarachnoid hemorrhage (HASH) is common, severe, and often refractory to conventional treatments. Current treatment standards include medications including opioids, until the pain is mitigated. Peripheral nerve blocks
Swarna Rajagopalan   +4 more
doaj   +1 more source

First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI) [PDF]

open access: yes, 2012
The objective of this pilot clinical study was to assess the safety, technical feasibility, pharmacokinetic (PK) profile and tumour response of DC Bead™ with irinotecan (DEBIRI™) delivered by intra-arterial embolisation for the treatment of metastatic ...
Eichler, Katrin   +6 more
core   +1 more source

Mechanistic Design of Graphdiyne‐Based Multimodal Sensing Integrating Machine Learning and Photothermal Dynamics for Precision Recognition and On‐Demand Inactivation

open access: yesAdvanced Science, EarlyView.
A triple‐mode theranostic platform enables integrated electrochemical, colorimetric, and photothermal detection of bacterial infection. Glucose oxidation triggers H2O2 generation and TMB oxidation to oxTMB, producing color and thermal signals under 808 nm NIR irradiation.
Jing Xu   +8 more
wiley   +1 more source

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