Results 91 to 100 of about 2,070,748 (278)
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Temperature Prediction of Road Anti-Frost Layer [PDF]
Journal of the Korean Society of Hazard Mitigation, 2019 Jaeho Son +3 more
openaire +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Experimental Study on Anti-Frosting Superhydrophobic Coatings for Energy Equipment Surfaces
SustainabilityWind and solar power generation represent crucial forms of clean energy utilisation, where generation efficiency is paramount. However, clean energy facilities such as wind turbine blades and photovoltaic sheets frequently cease operation during low temperatures due to ice and frost accumulation, resulting in energy wastage. This study investigates the
Haoran Li +4 more
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
FROSTING IN MEMBRANE ENERGY EXCHANGERS [PDF]
, 2016 Frost formation in heat/energy exchangers is undesirable because it may reduce air flow through the exchanger, increase the power consumption of fans, decrease the effectiveness of the exchanger, and in extreme cases, cause physical damage to the ...
Rafatinasr, Mohammad 1985-
core
Experimental Investigation on Frost Formation on Cold Surface under Natural Convection Conditions
Zhileng xuebao, 2019 A microscopic visualization method was applied experimentally, where comparative observations of frosting processes were conductedunder the same conditionson bare aluminum and hydrophobic surface with contact angles of 78° and 141°, respectively.
Zhou Shengqi +3 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab +19 more
wiley +1 more source